Skip to main content
MedVellum
QuestionsVideosPricing

MedVellum

Fellowship exam preparation across every specialty: source-verified topics, questions in every format, and videos.

Product

  • Specialties
  • Questions
  • Videos
  • Exam tools
  • Pricing

Verification & policy

  • Verified register
  • Editorial policy
  • Privacy
  • Terms

Account

  • Sign in
  • Create account
  • Dashboard
  • Account & billing

© 2026 MedVellum. For education only — not a substitute for clinical judgement.

llms.txtPsychiatry LLM catalogSitemap

Gen Surg Casessurgical-critical-care

Gen Surg Cases · surgical-critical-care

Post-laparotomy shock with AKI, refeeding risk and hyperglycaemia — feed, bridge, restrict and cap

Fellowship clinical-management station on surgical ICU nutrition: trophic enteral dosing, EPaNIC parenteral timing, NUTRIREA-2 shock-gut bridging, EFFORT protein restraint in AKI, refeeding restriction, NICE-SUGAR glucose caps, prokinetics and tube routing.

clinical-management1 min readVerification in progress

Target exams

FRACSFRCS(Gen Surg)ABSFRCSC
On this page
Study tools

Target exams

FRACSFRCS(Gen Surg)ABSFRCSC
Prompt
A 58-year-old man is day 2 after emergency laparotomy for perforated diverticulitis with washout and drain: low-dose noradrenaline, lactate 3.1, distended abdomen without stool, nasogastric output 400 mL, new oliguric kidney injury, 8 starved days with phosphate falling since feeds started, glucose 12 to 15 on steroids and sepsis. The candidate must choose enteral dose, time any parenteral support, bridge or advance through shock gut, dose protein for AKI, restrict for refeeding physiology, cap glucose, and manage intolerance and tube route.

Management walkthrough

Resuscitation and perfusion first — nutrition serves recovery, never precedes it. He is in vasopressor-dependent shock with a tenuous post-laparotomy abdomen: complete resuscitation, confirm source control, and read the abdomen (distension, drain output, stool, flatus, lactate trajectory) before any feeding rate is chosen. Shock owns pressors and perfusion targets — this station owns what follows.[11]

Start enteral trophic, withhold PN, bridge only if shock escalates. Begin low-volume EN now and advance on tolerance and perfusion: EDEN and PermiT both tied full against moderate delivery on death with less intolerance on the moderate side.[1][3] Do not top up with PN on day 2: EPaNIC favours day-8 initiation with faster recovery and fewer infections.[6] If noradrenaline escalates with rising lactate and an unpassed abdomen, stop advancing EN and bridge with PN — NUTRIREA-2 showed forced isocaloric EN in shock raised bowel ischaemia without survival gain.[11]

Dose protein for the AKI, restrict for the phosphate fall. Oliguric kidney injury means usual-dose protein, not 2.2 g per kg per day: EFFORT harm concentrated in AKI with RR 1.4 for 60-day death.[13] Eight starved days plus a post-feed phosphate fall means temporary macronutrient restriction with electrolyte repletion: the refeeding trial improved day-60 survival to 91 percent, and relative phosphate falls mark early-PN harm.[21][9]

Cap glucose, prokinet intolerance, route for delivery. Hold glucose at 180 or less with frequent measurement — intensive 81-to-108 targeting raised death with thirteen-fold severe hypoglycaemia.[25] Treat high residuals with prokinetics (moderate-certainty intolerance reduction) and consider postpyloric placement for delivery shortfalls — never as pneumonia prevention, which it is not.[29][27]

Close with disposition and honesty. Daily intensivist, surgical, dietetic and pharmacy review of perfusion, tolerance, phosphate and glucose until stable ward feeding resumes. Name the gaps: no verified calorie formula, no adult residual cutoff, and guideline recommendations mostly on moderate evidence or expert opinion — individualise and document why.[31]

References11ShowHide
  1. [11]Reignier J, Boisramé-Helms J, Brisard L, et al. Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet, 2018.PMID 29128300
  2. [1]Rice TW, Wheeler AP, Thompson BT, et al. Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA, 2012.PMID 22307571
  3. [3]Arabi YM, Aldawood AS, Haddad SH, et al. Permissive Underfeeding or Standard Enteral Feeding in Critically Ill Adults. N Engl J Med, 2015.PMID 25992505
  4. [6]Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med, 2011.PMID 21714640
  5. [13]Heyland DK, Patel J, Compher C, et al. The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial. Lancet, 2023.PMID 36708732
  6. [21]Doig GS, Simpson F, Heighes PT, et al. Restricted versus continued standard caloric intake during the management of refeeding syndrome in critically ill adults: a randomised, parallel-group, multicentre, single-blind controlled trial. Lancet Respir Med, 2015.PMID 26597128
  7. [9]Lauwers C, Langouche L, Wouters PJ, et al. Early phosphate changes as potential indicator of unreadiness for artificial feeding: a secondary analysis of the EPaNIC RCT. Crit Care, 2025.PMID 39875953
  8. [25]Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med, 2009.PMID 19318384
  9. [29]Lewis K, Alqahtani Z, Mcintyre L, et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. Crit Care, 2016.PMID 27527069
  10. [27]Zhang Z, Xu X, Ding J, et al. Comparison of postpyloric tube feeding and gastric tube feeding in intensive care unit patients: a meta-analysis. Nutr Clin Pract, 2013.PMID 23614960
  11. [31]Reignier J, Gaillard-Le Roux B, Dequin PF, et al. Expert consensus‑based clinical practice guidelines for nutritional support in the intensive care unit: the French Intensive Care Society (SRLF) and the French-Speaking Group of Pediatric Emergency Physicians and Intensivists (GFRUP). Ann Intensive Care, 2025.PMID 40665004
PreviousPost-laparotomy oozing with consumption — bleeding DIC, JAAM-2 start, product resuscitationsurgical-critical-careNextPostoperative healthcare-associated intra-abdominal infection after colectomy — shock predictors, urgent control, and the rescue pathwaysurgical-critical-care