GP · gastrointestinal-health
Bowel cancer screening and FOBT follow-up
Also known as Bowel cancer screening · FOBT · FIT · National Bowel Cancer Screening Program
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Overview
Bowel cancer is one of Australia's commonest cancers; in 2025 an estimated 6,941 people aged 50–74 were diagnosed (about 47% of all bowel cancers) and 1,779 died of the disease. Screening exists because the disease offers a long preclinical window: detect and remove the adenoma and the cancer never arrives.[15]
The National Bowel Cancer Screening Program began in August 2006 and mails a free immunochemical faecal occult blood test every two years to Australians aged 50–74; since 1 July 2024 those aged 45–49 have also been able to request a kit through the National Cancer Screening Register, though the youngest cohort sits outside the core performance indicators for now. About 14.3 million tests have been completed and at least 17,378 bowel cancers diagnosed through screening; programme participants who were later diagnosed with bowel cancer had lower death risk and less advanced disease.[15] Yet participation was only 42.0% in the 2023–2024 round, against 83.5% re-participation among previous participants — the first kit is the hard one, and the gap between a working programme and a finished job is the general practice waiting room.[15]
Risk shapes the pathway around the programme. A single first-degree relative diagnosed before 55, or two affected relatives, moves a person from population screening into colonoscopic surveillance at earlier ages and shorter intervals. Lynch syndrome — suspected on family-history criteria or found through universal tumour mismatch-repair testing — carries metachronous cancer risk after segmental colectomy and demands lifelong intensive surveillance.[14]
References15ShowHide
- [1]Hewitson P et al. Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update. Am J Gastroenterol, 2008.PMID 18479499
- [2]Corley DA et al. Adenoma detection rate and risk of colorectal cancer and death. N Engl J Med, 2014.PMID 24693890
- [3]Pin Vieito N et al. High-risk symptoms and quantitative faecal immunochemical test accuracy: Systematic review and meta-analysis. World J Gastroenterol, 2019.PMID 31148909
- [4]Phuangrach N et al. The Accuracy of Fecal Immunochemical Test in Colorectal Cancer Screening: A Meta-Analysis. Asian Pac J Cancer Prev, 2022.PMID 35345344
- [5]Selby K et al. Influence of Varying Quantitative Fecal Immunochemical Test Positivity Thresholds on Colorectal Cancer Detection: A Community-Based Cohort Study. Ann Intern Med, 2018.PMID 30242328
- [6]Levin TR et al. Effects of Organized Colorectal Cancer Screening on Cancer Incidence and Mortality in a Large Community-Based Population. Gastroenterology, 2018.PMID 30031768
- [7]Selby K et al. Program Components and Results From an Organized Colorectal Cancer Screening Program Using Annual Fecal Immunochemical Testing. Clin Gastroenterol Hepatol, 2022.PMID 33010408
- [8]Perry N et al. Optimising SMS content for bowel cancer screening participation in Australia: cross-sectional national survey findings. Public Health Res Pract, 2026.PMID 42112944
- [9]Lofti-Jam KL et al. Increasing bowel cancer screening participation: integrating population-wide, primary care and more targeted approaches. Public Health Res Pract, 2019.PMID 31384890
- [10]Song JH et al. Strategies to improve screening colonoscopy quality for the prevention of colorectal cancer. Korean J Intern Med, 2024.PMID 38247125
- [11]Hsu WF et al. Risk of colonoscopy-related complications in a fecal immunochemical test-based population colorectal cancer screening program. Endoscopy, 2022.PMID 33271603
- [12]Shanahan JJ et al. Characteristics of Interval Colorectal Cancer: A Canadian Retrospective Population-Level Analysis from Newfoundland and Labrador. Curr Oncol, 2022.PMID 36547130
- [13]Grogan P et al. Improving colonoscopy prioritisation and promoting the National Bowel Cancer Screening Program: keys to reducing bowel cancer burden. Public Health Res Pract, 2023.PMID 36918394
- [14]Kim TJ et al. Survival Outcome and Risk of Metachronous Colorectal Cancer After Surgery in Lynch Syndrome. Ann Surg Oncol, 2017.PMID 27766559
- [15]Smith SJ et al. Interval Cancer Characteristics, Staging and Survival Among National Bowel Cancer Screening Program Participants, Western Australia, 2018: A Retrospective Observational Cohort Study. Med J Aust, 2026.PMID 41629194