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GP KFPs / SAQsmental-health

GP KFPs / SAQs · mental-health

Perinatal mental health — KFP-style written assessment

KFP-style staged scenarios on perinatal mental health: distinguishing baby blues from PND from puerperal psychosis, EPDS screening and interpretation, sertraline in breastfeeding, antidepressant discontinuation relapse risk in pregnancy, and previous postpartum psychosis pregnancy planning.

30 marks45 min3 min readVerification in progress

Target exams

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Target exams

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Prompt
Perinatal mental health: the blues-PND-psychosis spectrum, screening with EPDS, sertraline in breastfeeding, and planning around postpartum psychosis

KFP 1 (10 marks)

A 28-year-old first-time mother is seen at her six-week postnatal check. She reports feeling tearful and overwhelmed since delivery but says she is 'coping'. EPDS score is 16. She denies thoughts of self-harm or harm to the baby. [1]

  1. Interpret her presentation and EPDS result. (4) [1]
  2. What is the most likely diagnosis? Justify against baby blues and puerperal psychosis. (4) [2]
  3. Outline your management plan. (2) [5]

Model answers

  1. EPDS score of 16 is above the cut-off of 13 suggesting probable depression. At six weeks postpartum with persistent symptoms beyond the baby blues window, this requires clinical assessment to confirm PND. She denies psychotic features or thoughts of harm — reassuring. [1] [2]
  2. Most likely postnatal depression: persistent low mood beyond two weeks (she is at six weeks) distinguishes it from self-limiting baby blues (day 3–5 peak, resolving within two weeks). No delusions or hallucinations about the baby distinguish it from puerperal psychosis. The EPDS screens — clinical assessment confirms. [1] [2]
  3. Offer CBT as first-line psychological therapy (network meta-analysis SMD −0.55 vs TAU across 78 RCTs). Consider SSRI if moderate-to-severe or if CBT unavailable; sertraline preferred in breastfeeding (87.4% infant levels below limit of detection). Book follow-up within two weeks; screen partner mental health. [5] [3]
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References5ShowHide
  1. [1]Cox JL, Holden JM, Sagovsky R Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry, 1987.PMID 3651732
  2. [2]Pinheiro E, Bogen DL, Hoxha D, Ciolino JD, Wisner KL Sertraline and breastfeeding: review and meta-analysis. Arch Womens Ment Health, 2015.PMID 25589155
  3. [3]Wesseloo R, Kamperman AM, Munk-Olsen T, Pop VJ, Kushner SA, Bergink V Risk of Postpartum Relapse in Bipolar Disorder and Postpartum Psychosis: A Systematic Review and Meta-Analysis. Am J Psychiatry, 2016.PMID 26514657
  4. [4]Bayrampour H, Kapoor A, Bunka M, Ryan D The Risk of Relapse of Depression During Pregnancy After Discontinuation of Antidepressants: A Systematic Review and Meta-Analysis. J Clin Psychiatry, 2020.PMID 32558401
  5. [5]Leng LL, Xiao W, He X, Wang T, Ning K Efficacy of psychological treatments for perinatal depression and anxiety: systematic review and network meta-analysis. Br J Psychiatry, 2026.PMID 42343881
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