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Q1: Definition and clinical presentation (2 min)
Define sebaceous hyperplasia. Describe the classical morphology, distribution and patient demographic. Why is the central dell such a useful clinical sign?
Q2: Differential diagnosis (3 min)
A 68-year-old presents with a 4 mm pearly papule on the nose. Walk the examiner through your differential diagnosis. Which single condition must you exclude, and how do you do it clinically and dermoscopically?
Q3: Investigations (2 min)
When is a biopsy mandatory in suspected sebaceous hyperplasia? Describe the pathognomonic dermoscopic features. What does histopathology show, and how does it differ from sebaceous adenoma?
Q4: Management (3 min)
Outline your stepwise management. Include destructive modalities (cryotherapy, electrodessication, laser) and the role, dose, monitoring and limitations of oral isotretinoin. How does the approach differ in a renal transplant recipient?
Q5: Complications, prognosis and Muir-Torre (3 min)
What is the natural history and recurrence rate after treatment? When would you suspect Muir-Torre syndrome, what is the screening workup, and which mismatch repair gene is most commonly implicated?