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Q1: Definition and clinical presentation (2 min)
What is herpes zoster? How does it typically present? Outline the prodrome, the rash morphology, and the timeline of vesicle evolution.
Q2: Differential diagnosis and special syndromes (3 min)
How do you differentiate zoster from herpes simplex and other vesicular eruptions? Describe herpes zoster ophthalmicus, Ramsay Hunt syndrome, and disseminated zoster.
Q3: Investigations (2 min)
What investigations are needed in an immunocompetent patient with classic dermatomal zoster? When would you order PCR, viral culture, HIV serology, or CSF analysis?
Q4: Management (3 min)
Outline the stepwise treatment: antiviral choice (aciclovir, valaciclovir, famciclovir), timing, dose, indications for IV therapy, the role of corticosteroids, and pain management.
Q5: Prevention and complications (2 min)
Describe the recombinant zoster vaccine (Shingrix) — efficacy, schedule, indications. Discuss post-herpetic neuralgia and how it is managed.