On this page
Study tools
Write your answer
Saved on this device. No marking — you are the marker.
Stem
A full-term neonate is noticed at birth to have widespread blistering, erosions, and areas of denuded skin over the trunk and limbs. The parents report that the skin seemed to blister with even gentle handling during delivery. On examination, there are erosions around the mouth and nares with moist granulation tissue, and the nails are absent. The infant is afebrile but has a weak cry and appears uncomfortable.
Questions
a) What is the most likely diagnosis, and how would you classify epidermolysis bullosa by the level of skin cleavage? (2 marks)
b) What investigations would you arrange to confirm the diagnosis and determine the subtype? (3 marks)
c) Outline your immediate management priorities for this neonate. (3 marks)
d) What are the major complications and prognostic factors in severe epidermolysis bullosa? (2 marks)