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Anaes TopicsThoracic anaesthesia

Anaes · Thoracic anaesthesia

Pulmonary hypertension and COPD in thoracic anaesthesia

Also known as Pulmonary hypertension anaesthesia · COPD thoracic surgery · Right ventricular failure · OLV in pulmonary hypertension

Perioperative management of pulmonary hypertension and COPD for thoracic surgery: RV physiology, haemodynamic goals, OLV risks, ventilation strategies, and crisis treatment of acute RV failure.

high3 referencesUpdated 26 July 20267 min readVerification in progress

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ANZCAFRCAABAEDAICFCAI

Red flags

  • Avoid increases in PVR: hypoxia, hypercapnia, acidosis, high airway pressures, pain, and hypothermia.
  • Support RV coronary perfusion: maintain SVR; avoid pure systemic vasodilation.
  • OLV may critically raise PVR and precipitate RV failure — have rescue plan.
  • Continue chronic PH therapies perioperatively when possible with specialist input.
  • COPD: optimise bronchodilators; protective ventilation; plan regional analgesia for cough.
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Practise this topic10 MCQs with explanations

Target exams

ANZCAFRCAABAEDAICFCAI

Red flags

  • Avoid increases in PVR: hypoxia, hypercapnia, acidosis, high airway pressures, pain, and hypothermia.
  • Support RV coronary perfusion: maintain SVR; avoid pure systemic vasodilation.
  • OLV may critically raise PVR and precipitate RV failure — have rescue plan.
  • Continue chronic PH therapies perioperatively when possible with specialist input.
  • COPD: optimise bronchodilators; protective ventilation; plan regional analgesia for cough.
The one-line answer

Pulmonary hypertension turns thoracic anaesthesia into a right ventricle problem. The RV is thin-walled and afterload-sensitive, and one-lung ventilation is the stress test that breaks it. The plan: keep PVR low (oxygenate, avoid acidosis and hypercapnia, minimise airway pressure), maintain SVR for RV coronary perfusion, never interrupt prostacyclin infusions, treat acute RV failure with oxygen, noradrenaline, and selective inhaled pulmonary vasodilators — and treat OLV as a timed exercise with a rescue plan.[1]

Meet the patient

A 72-year-old with severe COPD and Group 3 pulmonary hypertension is listed for a right upper lobectomy. The echo shows a dilated RV with reduced TAPSE. She is on home oxygen at 2 L and her baseline SpO2 is 91 percent. The surgeon wants to know if you are happy to proceed.[1]

The question is not whether you can induce her — it is whether the RV will survive one-lung ventilation. The right ventricle in pulmonary hypertension lives one hypoxic, hypercapnic, high-airway-pressure minute from failure, and OLV is all three at once. Your whole plan exists to defend that RV.[3]

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References3ShowHide
  1. [1]Minai OA et al. Perioperative risk and management in patients with pulmonary hypertension Chest, 2013.PMID 23880683
  2. [2]Brassard CL et al. Step-by-step clinical management of one-lung ventilation: continuing professional development Can J Anaesth, 2014.PMID 25389025
  3. [3]Karzai W, Schwarzkopf K. Hypoxemia during one-lung ventilation: prediction, prevention, and treatment Anesthesiology, 2009.PMID 19417615

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