Anaes · Ophthalmic anaesthesia
Ophthalmic drugs with systemic effects for the anaesthetist
Also known as Ophthalmic drugs with systemic effects for the anaesthetist · Eye drop systemic toxicity · Timolol phenylephrine echothiophate
Exam-exhaustive systemic effects of ophthalmic medications for ANZCA Final: absorption via the nasolacrimal route, timolol beta-blockade, phenylephrine hypertensive crisis, echothiophate-suxamethonium interaction, acetazolamide acid-base effects, mydriatic delirium, and anaesthetic decision rules.
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10 MCQs with explanations
Target exams
Red flags
Meet the patient
A 78-year-old man on timolol 0.5 percent drops and oral bisoprolol arrives for cataract extraction under sub-Tenon block with light sedation. After the midazolam his heart rate is 42 and his blood pressure 88 over 50. The list is only an eye case — which is exactly why nobody asked about the yellow bottle in his pocket.[2]
The two questions that decide his next five minutes are the two that decide every ophthalmic drug crisis: what is on this eye, and when was the last drop? Hold those two and the four-drug map below slots into place.[2]
You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Anaesthesia fellowship atlas.
References3Show ledgerHide ledger
- [1]Devereaux PJ, Yang H, Yusuf S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial Lancet, 2008.PMID 18479744
- [2]Lee TH, Marcantonio ER, Mangione CM, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery Circulation, 1999.PMID 10477528
- [3]Martyn JA, Richtsfeld M Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms Anesthesiology, 2006.PMID 16394702