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Anaes TopicsNeuraxial anaesthesia

Anaes · Neuraxial anaesthesia

Spinal (intrathecal) anaesthesia

Also known as Spinal anaesthesia · Subarachnoid block · Intrathecal anaesthesia · Spinal block · Single-shot spinal · Hyperbaric bupivacaine spinal

Spinal anaesthesia is the injection of a small dose of local anaesthetic into the cerebrospinal fluid of the subarachnoid space to produce a rapid, dense and predictable block of the sensory, motor and sympathetic nerves that the solution reaches. It is the standard anaesthetic for lower-body surgery and caesarean section, and its mastery rests on the anatomy of the neuraxial approach, the determinants of block height, the physiology of the sympathetic block and its hypotension, and the prevention and management of the post-dural puncture headache and the high spinal.

high11 referencesUpdated 26 July 202624 min readVerification in progress

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ANZCAFRCAABAEDAICFCAIFCA_SA

Red flags

  • Hypotension after spinal anaesthesia reflects the sympathetic block and can be profound, especially in the obstetric or volume-depleted patient; anticipate it with vasopressor and a colloid co-load and treat early and proactively.
  • A rising block above the fourth thoracic dermatome produces bradycardia, hypotension and respiratory compromise — a high spinal; support the circulation and ventilation until the block recedes.
  • A postural headache worse on standing and relieved by lying flat after a dural puncture is a post-dural puncture headache until proven otherwise; a fine pencil-point needle and a single dural puncture reduce its incidence.
  • Severe back pain with a new and progressive neurological deficit after a spinal is an epidural haematoma or abscess until proven otherwise; it is a surgical emergency demanding urgent imaging and decompression.
  • Profound bradycardia or asystole shortly after a high spinal in a young, fit, hypovolaemic or obstetric patient may be the Bezold-Jarisch reflex; treat with vasopressor, fluid and atropine and avoid the head-up position.
  • Coagulopathy, therapeutic anticoagulation outside the recommended intervals, infection at the puncture site and patient refusal are the principal contraindications; in the anticoagulated obstetric patient the SOAP consensus guides timing.
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

ANZCAFRCAABAEDAICFCAIFCA_SA

Red flags

  • Hypotension after spinal anaesthesia reflects the sympathetic block and can be profound, especially in the obstetric or volume-depleted patient; anticipate it with vasopressor and a colloid co-load and treat early and proactively.
  • A rising block above the fourth thoracic dermatome produces bradycardia, hypotension and respiratory compromise — a high spinal; support the circulation and ventilation until the block recedes.
  • A postural headache worse on standing and relieved by lying flat after a dural puncture is a post-dural puncture headache until proven otherwise; a fine pencil-point needle and a single dural puncture reduce its incidence.
  • Severe back pain with a new and progressive neurological deficit after a spinal is an epidural haematoma or abscess until proven otherwise; it is a surgical emergency demanding urgent imaging and decompression.
  • Profound bradycardia or asystole shortly after a high spinal in a young, fit, hypovolaemic or obstetric patient may be the Bezold-Jarisch reflex; treat with vasopressor, fluid and atropine and avoid the head-up position.
  • Coagulopathy, therapeutic anticoagulation outside the recommended intervals, infection at the puncture site and patient refusal are the principal contraindications; in the anticoagulated obstetric patient the SOAP consensus guides timing.
The one-line answer

Spinal (intrathecal) anaesthesia is the injection of a small dose of local anaesthetic into the CSF of the subarachnoid space, producing a rapid, dense and predictable block. The standard agent is hyperbaric bupivacaine 0.5 percent in 8 percent glucose, twelve-and-a-half to fifteen milligrams, giving a surgical block within five to ten minutes that lasts about two hours. Mastery rests on four ideas: the anatomy of the layers and the safe interspace below the conus; the baricity and position that set the block height; the sympathetic block that drives the hypotension; and the prevention and management of the complications — above all spinal-induced hypotension, the post-dural puncture headache and the high spinal.[1]

Meet the patient

A 32-year-old woman arrives for an elective caesarean. You sit her up, raise a wheal of 1 percent lidocaine, and pass a 27-gauge pencil-point needle into the subarachnoid space at L3/L4. Clear CSF flows. You inject 12.5 milligrams of hyperbaric bupivacaine with 15 micrograms of fentanyl, turn her supine with a left wedge, and start a phenylephrine infusion. Within ten minutes she is numb to T4 and comfortable; her baby is delivered awake and her systolic never strays far from baseline.[1]

That case is the synthesis of the whole topic: a small dose into the CSF, the baricity shaped by position, the hypotension anticipated by a co-load and a vasopressor, and the complications prevented by a fine pencil-point needle. Master those four and you have the spinal.[1]

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References11ShowHide
  1. [1]Ferré F, Martin C, Bosch L, et al. Control of Spinal Anesthesia-Induced Hypotension in Adults. Local Reg Anesth, 2020.PMID 32581577
  2. [2]Lee A, Ngan Kee WD, Gin T A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg, 2002.PMID 11916798
  3. [3]Veeser M, Hofmann T, Roth R, et al. Vasopressors for the management of hypotension after spinal anesthesia for elective caesarean section. Systematic review and cumulative meta-analysis. Acta Anaesthesiol Scand, 2012.PMID 22313496
  4. [4]Ngan Kee WD, Lee SWY, Ng FF, Khaw KS Prophylactic Norepinephrine Infusion for Preventing Hypotension During Spinal Anesthesia for Cesarean Delivery Anesth Analg, 2018.PMID 28678073
  5. [5]Palmer CM, Emerson S, Volgoropolous D, Alves D Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology, 1999.PMID 9952150
  6. [6]Sachs A, Smiley R Post-dural puncture headache: the worst common complication in obstetric anesthesia. Semin Perinatol, 2014.PMID 25146108
  7. [7]Cook TM, Counsell D, Wildsmith JA; Royal College of Anaesthetists Third National Audit Project Major complications of central neuraxial block: report on the Third National Audit Project of the Royal College of Anaesthetists. Br J Anaesth, 2009.PMID 19139027
  8. [8]Leffert L, Butwick A, Carvalho B, et al. The Society for Obstetric Anesthesia and Perinatology Consensus Statement on the Anesthetic Management of Pregnant and Postpartum Women Receiving Thromboprophylaxis or Higher Dose Anticoagulants. Anesth Analg, 2018.PMID 29099429
  9. [9]Uppal V, Shanthanna H, Prabhakar C, McKeen DM Intrathecal hyperbaric versus isobaric bupivacaine for adult non-caesarean-section surgery: systematic review protocol. BMJ Open, 2016.PMID 27194318
  10. [10]Sserunkuuma B, Olowo S, Tibaijuka L, et al. Prevalence, factors associated, and adverse maternal outcomes of spinal induced hypotension among mothers undergoing caesarean section at a tertiary hospital South-Western Uganda. BMC Anesthesiol, 2026.PMID 42363034
  11. [11]Wan JX, Zeng SS, Li JM, et al. Comparing the efficacy and safety of unilateral versus bilateral spinal anesthesia: a meta-analysis and systematic review. Ann Med, 2026.PMID 42314657

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