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Anaes TopicsRegional anaesthesia

Anaes · Regional anaesthesia

Interscalene brachial plexus block

Also known as Interscalene block · ISB · Shoulder block · Interscalene brachial plexus block

Exam-exhaustive interscalene block: indications for shoulder surgery, C5–C7 coverage with ulnar spare, near-universal phrenic palsy, pneumothorax and LAST risks, low-volume and superior-trunk alternatives, and ultrasound technique for ANZCA Final and equivalents.

high6 referencesUpdated 26 July 20267 min readVerification in progress

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Target exams

ANZCAFRCAABAEDAICFCAI

Red flags

  • Ipsilateral hemidiaphragmatic paresis is expected — contraindicated if the patient cannot tolerate loss of one hemidiaphragm (severe respiratory disease, contralateral phrenic palsy).
  • Vertebral/carotid intravascular injection can produce rapid LAST — aspirate, fractionate, lipid available.
  • Medial needle trajectory risks neuraxial spread; caudal trajectory risks pneumothorax.
  • Ulnar (C8–T1) sparing — wrong block for hand/forearm surgery.
  • Horner syndrome and recurrent laryngeal nerve block are usually transient but require counselling.
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Saved on this device.

Practise this topic20 MCQs with explanations

Target exams

ANZCAFRCAABAEDAICFCAI

Red flags

  • Ipsilateral hemidiaphragmatic paresis is expected — contraindicated if the patient cannot tolerate loss of one hemidiaphragm (severe respiratory disease, contralateral phrenic palsy).
  • Vertebral/carotid intravascular injection can produce rapid LAST — aspirate, fractionate, lipid available.
  • Medial needle trajectory risks neuraxial spread; caudal trajectory risks pneumothorax.
  • Ulnar (C8–T1) sparing — wrong block for hand/forearm surgery.
  • Horner syndrome and recurrent laryngeal nerve block are usually transient but require counselling.
The one-line answer

The interscalene block is the shoulder block — dense C5–C7 analgesia for shoulder and proximal humerus surgery, bought at the price of a near-universal ipsilateral hemidiaphragmatic paresis and an ulnar (C8–T1) sparing that makes it the wrong block for the hand. Use ultrasound and the lowest effective volume, counsel the phrenic cost, and reach for a diaphragm-sparing alternative — low-volume interscalene or superior trunk — when the patient cannot spare a hemidiaphragm.[1]

Meet the patient

A sixty-eight-year-old with severe chronic obstructive pulmonary disease is listed for arthroscopic rotator cuff repair, and the surgeon would like a regional block for analgesia. The block that fits the surgery is the interscalene block; the problem is that the same block paralyses half her diaphrag — and her lungs cannot spare it.[1]

The two questions that decide her plan are the two that decide every interscalene: will this block cover the surgery? (it will — shoulder is its home territory) and can her diaphrag take the hit? (it cannot, so you reach for a diaphragm-sparing alternative). Hold those two and the technique below slots into place.[1]

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References6ShowHide
  1. [1]Riazi S, Carmichael N, Awad I, et al. Effect of local anaesthetic volume (20 vs 5 ml) on the efficacy and respiratory consequences of ultrasound-guided interscalene brachial plexus block. Br J Anaesth, 2008.PMID 18682410
  2. [2]da Cunha DF, et al. Incidence of hemidiaphragmatic paralysis in superior trunk versus interscalene block upper limb surgeries: a systematic review, meta-analysis, and trial sequential analysis Anesth Pain Med (Seoul), 2026.PMID 42130052
  3. [3]Verbeke AL, et al. The diaphragm-sparing effect of interscalene block with a low-volume of ropivacaine 0.1% vs. 0.5%: A double-blind, controlled, randomised trial. Eur J Anaesthesiol Intensive Care, 2026.PMID 42244823
  4. [4]Neal JM, et al. The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity: Executive Summary 2017. Reg Anesth Pain Med, 2018.PMID 29356773
  5. [5]Albrecht E, Renard Y, Desai N Intravenous versus perineural dexamethasone to prolong analgesia after interscalene brachial plexus block: a systematic review with meta-analysis and trial sequential analysis. Br J Anaesth, 2024.PMID 38782616
  6. [6]Franco CD, Williams JM Ultrasound-Guided Interscalene Block: Reevaluation of the "Stoplight" Sign and Clinical Implications. Reg Anesth Pain Med, 2016.PMID 27203394

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