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Anaes TopicsAirway management

Anaes · Airway management

Supraglottic airway devices (LMA and SGAD): generations, applications and the difficult-airway rescue

Also known as Laryngeal mask airway · LMA · Classic LMA · ProSeal LMA · LMA Supreme · i-gel · Intubating LMA · Fastrach · Second-generation supraglottic airway device · SGAD

Supraglottic airway devices (SGADs) sit above the glottis and provide a hands-free airway without tracheal intubation, and they are the most frequently examined single piece of airway equipment because they straddle routine practice and the rescue algorithm. The framework rests on four ideas: the device forms a seal around the laryngeal inlet and leaves the hands free, but it is not a definitive airway; the first-generation classic LMA has an inflatable cuff, a lower seal pressure, and no gastric drainage channel; the second generation (ProSeal LMA, LMA Supreme, i-gel) achieves a higher seal — an adult network meta-analysis of 108 studies found oropharyngeal leak pressures higher by a mean 3.98 to 9.18 cm H2O versus the classic device — and adds a gastric drainage channel that permits gastric-tube placement, though routine placement has uncertain benefit at low-to-very-low certainty; and the devices are the guideline's supraglottic-airway rescue after failed intubation (second generation recommended), a fibreoptic-guided bridge to intubation, and an option in CPR, prehospital and paediatric anaesthesia. Anchored to contemporary evidence on gastric-tube placement through the second-generation drainage channel, the non-inflatable visual laryngeal mask, the sevoflurane concentration for i-gel insertion in children, the difficult airway of spinal muscular atrophy, and the physiological emergency airway.

high11 referencesUpdated 26 July 202612 min readVerification in progress

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Red flags

  • A supraglottic airway is NOT a definitive airway. It does not isolate the trachea from the oesophagus, and it does not fully protect against aspiration — most importantly in the first-generation device, which has no gastric drainage channel. Reserve the elective use for fasted patients at low aspiration risk, and prefer a second-generation device with a gastric channel whenever the risk is borderline.
  • The classic LMA has the lowest seal of the family — second-generation devices achieve higher oropharyngeal leak pressures (mean differences about +4 to +9 cm H2O in an adult network meta-analysis). In the patient with low pulmonary compliance or high airway resistance — obesity, bronchospasm, the head-down laparoscopic position — peak airway pressures exceed the lower seal and the device vents, leaks, and fails to ventilate. A second-generation device or an endotracheal tube is required.
  • Displacement is the silent failure of the supraglottic airway. The device can rotate, migrate, or be knocked out during positioning, surgery, or transfer, and the leak that follows is easily missed without continuous capnography — in NAP4's ICU and emergency cases, failure to use capnography contributed to 74% of death-or-brain-damage events. Use continuous waveform capnography for every case managed with a supraglottic device.
  • In the unanticipated failed intubation, the SGAD is the guideline's supraglottic-airway RESCUE (second generation recommended). If oxygenation is inadequate after SGAD placement, do not persist — proceed to front-of-neck access (scalpel cricothyroidotomy is the recommended rescue technique). Oxygenation that is adequate after the SGAD is a reason to stop, wake the patient, and not to persist with repeated attempts at intubation.
  • High aspiration risk — the full stomach, obesity, pregnancy, gastro-oesophageal reflux disease, ileus, and the upper-airway obstruction or bowel obstruction — is a relative contraindication to a first-generation device and an indication for a rapid sequence induction with an endotracheal tube. The second-generation gastric channel partially mitigates but does not abolish the risk.
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Red flags

  • A supraglottic airway is NOT a definitive airway. It does not isolate the trachea from the oesophagus, and it does not fully protect against aspiration — most importantly in the first-generation device, which has no gastric drainage channel. Reserve the elective use for fasted patients at low aspiration risk, and prefer a second-generation device with a gastric channel whenever the risk is borderline.
  • The classic LMA has the lowest seal of the family — second-generation devices achieve higher oropharyngeal leak pressures (mean differences about +4 to +9 cm H2O in an adult network meta-analysis). In the patient with low pulmonary compliance or high airway resistance — obesity, bronchospasm, the head-down laparoscopic position — peak airway pressures exceed the lower seal and the device vents, leaks, and fails to ventilate. A second-generation device or an endotracheal tube is required.
  • Displacement is the silent failure of the supraglottic airway. The device can rotate, migrate, or be knocked out during positioning, surgery, or transfer, and the leak that follows is easily missed without continuous capnography — in NAP4's ICU and emergency cases, failure to use capnography contributed to 74% of death-or-brain-damage events. Use continuous waveform capnography for every case managed with a supraglottic device.
  • In the unanticipated failed intubation, the SGAD is the guideline's supraglottic-airway RESCUE (second generation recommended). If oxygenation is inadequate after SGAD placement, do not persist — proceed to front-of-neck access (scalpel cricothyroidotomy is the recommended rescue technique). Oxygenation that is adequate after the SGAD is a reason to stop, wake the patient, and not to persist with repeated attempts at intubation.
  • High aspiration risk — the full stomach, obesity, pregnancy, gastro-oesophageal reflux disease, ileus, and the upper-airway obstruction or bowel obstruction — is a relative contraindication to a first-generation device and an indication for a rapid sequence induction with an endotracheal tube. The second-generation gastric channel partially mitigates but does not abolish the risk.
The one-line answer

A supraglottic airway device sits above the glottis, seals around the laryngeal inlet, and frees the anaesthetist's hands — but it is never a definitive airway. The first-generation classic LMA has the lowest seal of the family and no gastric channel; the second generation (ProSeal, Supreme, i-gel) achieves a higher seal — oropharyngeal leak pressures higher by a mean 3.98 to 9.18 cm H2O versus the classic device across 108 studies and 10,645 adults — and carries a gastric drainage channel. Reserve it for the fasted, low-risk patient — and reach for a second-generation device as the guideline's supraglottic-airway rescue when intubation fails.[9][7]

Meet the patient

A fit, fasted 45-year-old arrives for a day-case knee arthroscopy — short case, spontaneous ventilation, no muscle relaxant needed. You plan a second-generation supraglottic airway so your hands are free for the surgical positioning, with continuous capnography running from placement — because in NAP4's ICU and emergency airway events, failure to use capnography contributed to 74% of death-or-brain-damage cases.[8]

The question every supraglottic-airway decision answers is threefold: can it seal at the airway pressure this lung demands, does it protect against aspiration, and is it the right tool if the airway turns difficult? Hold those three, and the whole device family sorts itself cleanly.[9]

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References11ShowHide
  1. [1]Yin X, et al. Gastric tube placement through the drainage channel of second-generation supraglottic airway devices: a systematic review with evidence mapping Front Surg, 2026.PMID 42344572
  2. [2]Migliorelli S, et al. Clinical Evaluation of a Non-inflatable Visual Laryngeal Mask Airway: A Prospective Service Assessment in Elective and Difficult Airway Management Cureus, 2026.PMID 42291977
  3. [3]Gan Z, et al. The Median Effective Concentration of Sevoflurane for I-Gel Laryngeal Mask Insertion in Unpremedicated Children Aged 1-10 Years: A Prospective Concentration-Finding Study Pediatr Discov, 2026.PMID 42021953
  4. [4]Black KM, et al. Anesthesia Care, Complications, and Airway Management for Patients With Spinal Muscular Atrophy: A Retrospective Chart Review From a Quaternary Children's Hospital Anesth Analg, 2026.PMID 42363899
  5. [5]Ghaffar S, et al. Physiological difficult airway management in the emergency department J Pak Med Assoc, 2026.PMID 42363338
  6. [6]Schramm D, et al. Bronchoscopic and interventional management of tracheobronchomalacia in children with bronchopulmonary dysplasia: a review of evidence Paediatr Respir Rev, 2026.PMID 42364941
  7. [7]Frerk C, et al. Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults. Br J Anaesth, 2015.PMID 26556848
  8. [8]Cook TM, et al. Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 2: intensive care and emergency departments. Br J Anaesth, 2011.PMID 21447489
  9. [9]Lai CJ, et al. Comparison of the efficacy of supraglottic airway devices in low-risk adult patients: a network meta-analysis and systematic review. Sci Rep, 2021.PMID 34301986
  10. [10]Mihara T, et al. A network meta-analysis of the clinical properties of various types of supraglottic airway device in children. Anaesthesia, 2017.PMID 28737223
  11. [11]Lim WY, et al. Awake supraglottic airway guided flexible bronchoscopic intubation in patients with anticipated difficult airways. Korean J Anesthesiol, 2019.PMID 31475506

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