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Anaes CasesPostoperative nausea & vomiting

Anaes Cases · Postoperative nausea & vomiting

The high-risk PONV patient for the laparoscopic surgery

The long case — the Apfel 4 (the female, the non-smoker, the PONV history, the expected opioid). The multicomponent prophylaxis (the dexamethasone, the ondansetron, the aprepitant), the TIVA, the opioid-sparing, the sugammadex, and the rescue plan.

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ANZCAFRCAABAEDAIC
Prompt
A 35-year-old non-smoking woman with the previous PONV for the laparoscopic gynaecological surgery. Discuss the prophylaxis plan.

Presentation

A 35-year-old non-smoking woman with the previous severe PONV after her caesarean section, for the elective laparoscopic ovarian cystectomy. Discuss the PONV prophylaxis plan.

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References2ShowHide
  1. [1]Dombrower R, et al. Perioperative Anesthesia Strategies for the Prevention of Postoperative Nausea and Vomiting Within Enhanced Recovery After Surgery Pathways: A Clinical Narrative Review. J Clin Med, 2026.PMID 42194789
  2. [2]Grigio TR, et al. Aprepitant and fosaprepitant as a prophylactic antiemetic for preventing postoperative nausea and vomiting after general anaesthesia: a systematic review and meta-analysis. Clinics, 2025.PMID 41100974
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PreviousThe intraoperative cardiac arrest — crisis resource managementPatient safety, human factors & CRMNextThe persistent PONV in the recovery roomPostoperative nausea & vomiting