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Anaes CasesNeuromuscular blockade & reversal

Anaes Cases · Neuromuscular blockade & reversal

The weak patient in recovery — residual neuromuscular blockade

The residual-blockade long case — recognising a train-of-four ratio below 0.9 despite an apparently awake patient, the unreliability of clinical tests, quantitative monitoring, and the management (oxygen, airway positioning, further reversal or ventilatory support). Anchored to the Naguib monitoring consensus.

long2 min readSource-verified ·

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ANZCAFRCAABAEDAIC
Prompt
A 68-year-old woman is in the recovery room after a 90-minute abdominal operation under a rocuronium-based general anaesthetic reversed with neostigmine. She is awake and obeys commands, but she is described as 'floppy' and her oxygen saturation is 92 per cent on room air. Discuss the diagnosis and management.

Presentation

A 68-year-old woman is in the recovery room after a 90-minute abdominal operation performed under a rocuronium-based general anaesthetic, reversed at the end with neostigmine 2.5 mg and glycopyrrolate. She is awake, opens her eyes and obeys commands, and can lift her head briefly on request. The recovery nurse reports, however, that she is "floppy," her breathing is shallow, and her oxygen saturation has drifted to 92 per cent on room air. She received no intra-operative neuromuscular monitoring.

[5]
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References3ShowHide
  1. [5]Naguib M, Brull SJ, Kopman AF, Hunter JM, et al. Consensus Statement on Perioperative Use of Neuromuscular Monitoring. Anesthesia & Analgesia, 2018.PMID 29200077
  2. [3]Abrishami A, Ho J, Wong J, Yin L, Chung F. Sugammadex, a selective reversal medication for preventing postoperative residual neuromuscular blockade. Cochrane Database of Systematic Reviews, 2009.PMID 19821409
  3. [6]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
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