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Anaes CasesIntravenous induction agents

Anaes Cases · Intravenous induction agents

Induction of anaesthesia in the shocked patient

The induction-in-shock long case — the agent choice (ketamine or etomidate, never propofol/thiopental for their hypotension), the reduced dose, the cardiovascular-sparing reasoning, and the etomidate-adrenal caveat weighed against ketamine.

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ANZCAFRCAABAEDAIC
Prompt
A 60-year-old man in septic shock (lactate 4, noradrenaline running, MAP 60) needs an emergency laparotomy for a perforated bowel. Discuss the choice of induction agent and dose.

Presentation

A 60-year-old man is in established septic shock from a perforated bowel: he is cool, confused, tachycardic at 120, the blood pressure is 95/50 on a rising noradrenaline infusion, the lactate is 4, and he needs an emergency laparotomy. The question is how to induce anaesthesia without precipitating a cardiovascular collapse.

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References1ShowHide
  1. [1]Albert SG, Ariyan S, Rather A. The effect of etomidate on adrenal function in critical illness: a systematic review. Intensive Care Medicine, 2011.PMID 21373823
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PreviousOxygen-refractory hypoxia after intubationApplied cardiovascular & respiratory physiologyNextKetamine in the head-injured patient — the overturned contraindicationIntravenous induction agents