Anaes Cases · Anaesthetic adjuncts
Dexmedetomidine-induced bradycardia
Short case — dexmedetomidine bradycardia. Reduce or stop; atropine; dose-dependent effect.
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ANZCAFRCAABAEDAIC
Prompt
On dexmedetomidine infusion for ICU sedation, the heart rate falls to 32. Manage.
Presentation
On dexmedetomidine infusion (1.0 mcg/kg/h) for ICU sedation after surgery, the heart rate falls from 70 to 32 and the blood pressure from 130/80 to 85/50. The patient is sedated but arousable. Manage.
References2ShowHide
- [1]Riker RR, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA, 2009.PMID 19188334
- [2]Gertler R, et al. Dexmedetomidine: a novel sedative-analgesic agent. Proc (Bayl Univ Med Cent), 2001.PMID 16369581