Acute Respiratory Distress - Paediatric
Summary
Acute respiratory distress in children is difficulty breathing or inadequate breathing, which can be caused by many conditions affecting the airways, lungs, or breathing muscles. Think of breathing as your child's body getting oxygen in and carbon dioxide out—when something interferes with this process (blocked airways, lung problems, breathing muscle weakness), your child has to work harder to breathe, causing respiratory distress. This is a medical emergency that can progress rapidly to respiratory failure (inability to breathe adequately) and death if not treated promptly. The most common causes vary by age—in infants, it's often bronchiolitis or pneumonia; in older children, it's often asthma, pneumonia, or croup. The presentation can be subtle in infants (may just be grunting, nasal flaring, or poor feeding) or more obvious in older children (obvious difficulty breathing). The key to management is recognizing respiratory distress early (increased work of breathing, tachypnea, use of accessory muscles, grunting, nasal flaring), assessing severity, providing immediate support (oxygen, positioning, may need ventilation), treating the underlying cause, and monitoring closely. Early recognition and treatment are crucial—respiratory distress can progress rapidly to respiratory failure.
Key Facts
- Definition: Difficulty breathing or inadequate breathing
- Incidence: Very common (thousands of cases/year)
- Mortality: Low (<1%) with prompt treatment, higher if delayed
- Peak age: Infants and young children (highest risk)
- Critical feature: Increased work of breathing, tachypnea, signs of distress
- Key investigation: Clinical assessment (usually sufficient)
- First-line treatment: Oxygen, treat underlying cause, may need ventilation
Clinical Pearls
"Work of breathing is key" — Look for increased work of breathing (use of accessory muscles, intercostal recession, subcostal recession, tracheal tug, head bobbing). This is more important than just the respiratory rate.
"Infants show different signs" — Infants may show subtle signs (grunting, nasal flaring, poor feeding) rather than obvious difficulty breathing. Always look for these signs in infants.
"Don't wait for cyanosis" — Cyanosis is a late sign. If a child is cyanotic, they're in severe respiratory failure. Treat before they become cyanotic.
"Respiratory distress can progress rapidly" — Children, especially infants, can deteriorate very quickly. Don't wait—if you suspect respiratory distress, assess and treat urgently.
Why This Matters Clinically
Respiratory distress is a medical emergency that can progress rapidly to respiratory failure and death if not treated promptly. Early recognition (especially in infants where signs may be subtle), immediate support (oxygen, positioning), and treating the underlying cause are essential. This is a condition that all clinicians caring for children need to recognize and manage urgently, as delayed treatment can be fatal.
Incidence & Prevalence
- Overall: Very common (thousands of cases/year)
- Trend: Stable (common condition)
- Peak age: Infants and young children (highest risk)
Demographics
| Factor | Details |
|---|---|
| Age | Highest risk in infants and young children (<5 years) |
| Sex | Varies by cause (asthma = slight male predominance) |
| Ethnicity | Higher in certain populations (asthma, etc.) |
| Geography | Higher in resource-poor settings |
| Setting | Emergency departments, pediatric ICU, hospitals |
Risk Factors
Non-Modifiable:
- Age (infants and young children = highest risk)
- Prematurity (higher risk)
- Chronic lung disease (higher risk)
Modifiable:
| Risk Factor | Relative Risk | Mechanism |
|---|---|---|
| Asthma | 5-10x | Airway obstruction |
| Infections | 3-5x | Pneumonia, bronchiolitis |
| Smoking exposure | 2-3x | Worsens respiratory conditions |
| No vaccinations | 2-3x | Increased infection risk |
Common Causes
| Cause | Frequency | Typical Patient |
|---|---|---|
| Bronchiolitis | 30-40% | Infants, winter |
| Asthma | 20-30% | Older children |
| Pneumonia | 15-20% | All ages |
| Croup | 10-15% | Young children |
| Other | 10-15% | Various |
The Respiratory Distress Mechanism
Step 1: Underlying Problem
- Airway obstruction: Blocked airways (asthma, croup, foreign body)
- Lung problems: Lung disease (pneumonia, bronchiolitis, ARDS)
- Breathing muscle weakness: Weak muscles (neuromuscular disease)
- Result: Breathing becomes difficult
Step 2: Increased Work of Breathing
- Compensation: Body tries to compensate
- Increased effort: Works harder to breathe
- Accessory muscles: Uses extra muscles
- Result: Increased work of breathing
Step 3: Clinical Manifestation
- Tachypnea: Fast breathing
- Signs of distress: Use of accessory muscles, recession, grunting
- Result: Respiratory distress visible
Step 4: Respiratory Failure (If Not Treated)
- Inadequate breathing: Can't breathe adequately
- Hypoxia: Low oxygen
- Hypercapnia: High carbon dioxide
- Result: Respiratory failure, death
Classification by Cause
| Cause | Mechanism | Clinical Features |
|---|---|---|
| Airway obstruction | Blocked airways | Stridor, wheeze, difficulty breathing |
| Lung disease | Lung problems | Tachypnea, crackles, difficulty breathing |
| Breathing muscle weakness | Weak muscles | Shallow breathing, difficulty breathing |
Anatomical Considerations
Respiratory System:
- Upper airways: Nose, mouth, throat
- Lower airways: Trachea, bronchi, lungs
- Breathing muscles: Diaphragm, intercostal muscles
Why Children are Vulnerable:
- Smaller airways: More easily blocked
- Less reserve: Less ability to compensate
- Rapid deterioration: Can deteriorate quickly
Symptoms: The Patient's Story
Typical Presentation:
Infants (May Be Subtle):
Older Children:
Signs: What You See
Vital Signs (Abnormal):
| Sign | Finding | Significance |
|---|---|---|
| Respiratory rate | High (tachypnea) | Respiratory distress |
| Heart rate | May be high (compensatory) | Tachycardia |
| SpO2 | May be low | Hypoxia |
| Temperature | May be elevated (if infection) | Fever |
General Appearance:
Respiratory Examination:
| Finding | What It Means | Frequency |
|---|---|---|
| Tachypnea | Fast breathing | Always |
| Use of accessory muscles | Working hard to breathe | 70-80% |
| Intercostal recession | Sucking in between ribs | 60-70% |
| Subcostal recession | Sucking in below ribs | 50-60% |
| Tracheal tug | Sucking in at neck | 40-50% |
| Head bobbing | Head bobbing with breathing (infants) | 30-40% (infants) |
| Grunting | Grunting sounds (infants) | 30-40% (infants) |
| Nasal flaring | Flaring nostrils | 40-50% |
| Cyanosis | Blue color (late sign) | 10-20% (if severe) |
Auscultation:
| Finding | What It Means | Frequency |
|---|---|---|
| Wheeze | Airway obstruction (asthma, bronchiolitis) | 40-50% |
| Crackles | Lung disease (pneumonia) | 30-40% |
| Stridor | Upper airway obstruction (croup) | 10-20% |
| Decreased air entry | Severe disease | 20-30% (if severe) |
Signs of Exhaustion (Critical):
Red Flags
[!CAUTION] Red Flags — Immediate Escalation Required:
- Severe respiratory distress — Medical emergency, needs urgent support
- Respiratory failure — Medical emergency, needs urgent ventilation
- Signs of exhaustion — Medical emergency, respiratory arrest imminent
- Cyanosis — Medical emergency, severe respiratory failure
- Altered mental status — Medical emergency, needs urgent assessment
- Signs of impending respiratory arrest — Medical emergency, needs urgent ventilation
Structured Approach: ABCDE
A - Airway
- Assessment: May be compromised (obstruction, decreased consciousness)
- Action: Secure if compromised (may need intubation)
B - Breathing
- Look: Increased work of breathing, signs of distress
- Listen: Wheeze, crackles, stridor, decreased air entry
- Measure: SpO2 (may be low), respiratory rate (usually high)
- Action: Oxygen urgently, may need ventilation
C - Circulation
- Look: May have signs of shock (if severe)
- Feel: Pulse (may be fast), BP (usually normal, may be low if severe)
- Listen: Heart sounds (usually normal)
- Measure: BP (usually normal), HR (may be high)
- Action: Monitor if severe
D - Disability
- Assessment: Mental status (may be altered if severe)
- Action: Assess if severe
E - Exposure
- Look: Respiratory examination, look for cause
- Listen: Auscultation
- Action: Complete examination, identify cause
Specific Examination Findings
Work of Breathing Assessment (Critical):
| Sign | Technique | Finding | Clinical Use |
|---|---|---|---|
| Accessory muscles | Look at neck, shoulders | Using extra muscles | Increased work |
| Intercostal recession | Look between ribs | Sucking in | Increased work |
| Subcostal recession | Look below ribs | Sucking in | Increased work |
| Tracheal tug | Look at neck | Sucking in | Increased work |
| Head bobbing | Look at head (infants) | Bobbing with breathing | Increased work (infants) |
| Grunting | Listen (infants) | Grunting sounds | Increased work (infants) |
| Nasal flaring | Look at nose | Flaring nostrils | Increased work |
Auscultation:
| Finding | What It Means | Clinical Use |
|---|---|---|
| Wheeze | Airway obstruction | Asthma, bronchiolitis |
| Crackles | Lung disease | Pneumonia |
| Stridor | Upper airway obstruction | Croup, foreign body |
| Decreased air entry | Severe disease | May need ventilation |
Special Tests
| Test | Technique | Positive Finding | Clinical Use |
|---|---|---|---|
| SpO2 | Pulse oximeter | Low (<92%) | Hypoxia |
| Respiratory rate | Count breaths | High (age-specific) | Tachypnea |
| Chest X-ray | If needed | May show cause | Identifies cause |
First-Line (Bedside) - Do Immediately
1. Clinical Assessment (Most Important)
- Work of breathing: Assess increased work
- Auscultation: Listen for wheeze, crackles, stridor
- Action: Usually sufficient for diagnosis and severity assessment
2. SpO2 (Essential)
- Purpose: Assess oxygenation
- Finding: May be low
- Action: Essential for monitoring
Laboratory Tests
| Test | Expected Finding | Purpose |
|---|---|---|
| Arterial blood gas | May show hypoxia, hypercapnia | Assesses gas exchange |
| Full Blood Count | May show leukocytosis (if infection) | Identifies infection |
| CRP | May be elevated (if infection) | Identifies infection |
Imaging
Chest X-Ray (If Needed):
| Indication | Finding | Clinical Note |
|---|---|---|
| Uncertain diagnosis | May show cause (pneumonia, etc.) | If needed to identify cause |
Diagnostic Criteria
Clinical Diagnosis:
- Increased work of breathing + tachypnea + signs of distress = Respiratory distress
Severity Assessment:
- Mild: Slight increase in work, good function
- Moderate: Obvious increase in work, some dysfunction
- Severe: Severe increase in work, exhaustion, respiratory failure
Management Algorithm
RESPIRATORY DISTRESS (CHILD)
(Difficulty breathing + signs of distress)
↓
┌─────────────────────────────────────────────────┐
│ IMMEDIATE ASSESSMENT (ABCDE) │
│ • Airway, Breathing, Circulation │
│ • Assess work of breathing │
│ • SpO2 (essential) │
│ • This is the priority │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ OXYGEN (URGENT) │
│ • High-flow oxygen │
│ • Don't wait—give oxygen immediately │
│ • Monitor SpO2 │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ IDENTIFY CAUSE │
│ • History, examination, auscultation │
│ • Chest X-ray if needed │
│ • Identify: asthma, pneumonia, bronchiolitis, etc. │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ TREAT UNDERLYING CAUSE │
├─────────────────────────────────────────────────┤
│ ASTHMA │
│ → Bronchodilators (salbutamol) │
│ → Steroids (prednisolone) │
│ │
│ PNEUMONIA │
│ → Antibiotics │
│ → Supportive care │
│ │
│ BRONCHIOLITIS │
│ → Supportive care │
│ → Oxygen │
│ │
│ CROUP │
│ → Steroids (dexamethasone) │
│ → Nebulized adrenaline if severe │
│ │
│ OTHER │
│ → Treat as appropriate │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ VENTILATION (IF NEEDED) │
│ • If respiratory failure │
│ • If exhausted │
│ • If SpO2 <92% despite oxygen │
│ • May need CPAP, BiPAP, or intubation │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ MONITOR & FOLLOW-UP │
│ • Monitor work of breathing │
│ • Monitor SpO2 │
│ • Reassess severity │
│ • Discharge when stable │
└─────────────────────────────────────────────────┘
Acute/Emergency Management - The First Hour
Immediate Actions (Do Simultaneously):
-
ABCs (Airway, Breathing, Circulation) - PRIORITY
- Airway: Secure if compromised
- Breathing: Assess work of breathing, auscultate
- SpO2: Check immediately
- Action: This is the priority
-
Oxygen (Urgent)
- High-flow oxygen: Give immediately
- Don't wait: Even before you know the cause
- Monitor SpO2: Target >92%
- Action: Support oxygenation
-
Identify Cause
- History: Recent illness, known conditions
- Examination: Auscultation, look for cause
- Chest X-ray: If needed
- Action: Guide treatment
-
Treat Underlying Cause
- Asthma: Bronchodilators, steroids
- Pneumonia: Antibiotics
- Bronchiolitis: Supportive care
- Croup: Steroids, nebulized adrenaline if severe
- Other: As appropriate
- Action: Address cause
-
Ventilation (If Needed)
- If respiratory failure: May need CPAP, BiPAP, or intubation
- If exhausted: May need ventilation
- Action: Support breathing if needed
Medical Management
Oxygen (Essential):
| Method | Indication | Notes |
|---|---|---|
| High-flow oxygen | All cases | Give immediately |
| CPAP | If moderate-severe | Non-invasive support |
| BiPAP | If moderate-severe | Non-invasive support |
| Intubation | If respiratory failure | Invasive ventilation |
Asthma Treatment (If Asthma):
| Drug | Dose | Route | Notes |
|---|---|---|---|
| Salbutamol | 2.5-5mg | Nebulized | Repeat as needed |
| Prednisolone | 1-2mg/kg (max 40mg) | PO | Daily for 3-5 days |
Pneumonia Treatment (If Pneumonia):
| Drug | Dose | Route | Notes |
|---|---|---|---|
| Amoxicillin | 50mg/kg (max 1g) | PO | TDS (if mild) |
| Co-amoxiclav | 30mg/kg (max 1.2g) | IV | TDS (if severe) |
Croup Treatment (If Croup):
| Drug | Dose | Route | Notes |
|---|---|---|---|
| Dexamethasone | 0.15mg/kg (max 10mg) | PO/IM | Single dose |
| Nebulized adrenaline | 5ml of 1:1000 | Nebulized | If severe |
Disposition
Admit to Hospital If:
- Moderate-severe: Needs monitoring, treatment
- ICU: If respiratory failure, needs ventilation
- Regular ward: If stable but needs monitoring
Discharge Criteria:
- Stable: No respiratory distress
- SpO2 normal: On room air or low-flow oxygen
- Able to take oral: If medications needed
- Clear plan: For continued treatment, follow-up
Follow-Up:
- Most recover: With appropriate treatment
- If asthma: Ongoing asthma management
- Long-term: Usually no long-term issues if treated promptly
Immediate (Hours-Days)
| Complication | Incidence | Presentation | Management |
|---|---|---|---|
| Respiratory failure | 5-10% (if severe) | Inability to breathe adequately | Ventilation |
| Respiratory arrest | 1-5% (if severe) | Stopped breathing | Resuscitation, ventilation |
| Death | <1% (with treatment) | If not treated promptly | Prevention through early treatment |
| Pneumothorax | Rare | Collapsed lung | Drainage |
Respiratory Failure:
- Mechanism: Inability to breathe adequately
- Management: Ventilation (CPAP, BiPAP, or intubation)
- Prevention: Early recognition, treatment
Early (Days-Weeks)
1. Usually Full Recovery (90-95%)
- Mechanism: Most recover with treatment
- Management: Usually no long-term treatment needed
- Prevention: Early treatment
2. Persistent Issues (5-10%)
- Mechanism: If underlying cause persists (asthma, etc.)
- Management: Ongoing management
- Prevention: Address underlying cause
Late (Months-Years)
1. Usually No Long-Term Issues (90-95%)
- Mechanism: Most recover completely
- Management: Usually no long-term treatment needed
- Prevention: N/A
Natural History (Without Treatment)
Untreated Respiratory Distress:
- High risk of respiratory failure: Almost certain if severe
- High mortality: If not treated promptly
- Poor outcomes: If not treated
Outcomes with Treatment
| Variable | Outcome | Notes |
|---|---|---|
| Recovery | 90-95% | Most recover with prompt treatment |
| Mortality | <1% | Very low with prompt treatment |
| Time to recovery | Hours to days | With treatment |
Factors Affecting Outcomes:
Good Prognosis:
- Early treatment: Better outcomes
- Mild-moderate: Usually recover quickly
- Treatable cause: Better outcomes
- No complications: Better outcomes
Poor Prognosis:
- Delayed treatment: Higher risk of respiratory failure
- Severe distress: Higher risk of respiratory failure
- Respiratory failure: Higher mortality
- Very young: May have worse outcomes
Prognostic Factors
| Factor | Impact on Prognosis | Evidence Level |
|---|---|---|
| Early treatment | Better outcomes | High |
| Severity | More severe = worse | High |
| Cause | Some causes worse | Moderate |
| Age | Very young = worse | Moderate |
Key Guidelines
1. BTS Guidelines (2019) — British guideline on the management of asthma. British Thoracic Society
Key Recommendations:
- Oxygen for all
- Bronchodilators for asthma
- Steroids for asthma
- Evidence Level: 1A
2. NICE Guidelines (2015) — Bronchiolitis in children: diagnosis and management. National Institute for Health and Care Excellence
Key Recommendations:
- Supportive care
- Oxygen if needed
- Evidence Level: 1A
Landmark Trials
Multiple studies on asthma treatment, oxygen use.
Evidence Strength
| Intervention | Level | Key Evidence | Clinical Recommendation |
|---|---|---|---|
| Oxygen | 1A | Universal | Essential |
| Bronchodilators (asthma) | 1A | Multiple RCTs | Essential for asthma |
| Steroids (asthma) | 1A | Multiple RCTs | Essential for asthma |
What is Respiratory Distress?
Respiratory distress is when your child has difficulty breathing or isn't breathing well enough. Think of breathing as your child's body getting oxygen in and carbon dioxide out—when something interferes with this (blocked airways, lung problems, weak breathing muscles), your child has to work harder to breathe, causing respiratory distress.
In simple terms: Your child is having trouble breathing and needs help. This is a medical emergency, but with prompt treatment, most children recover completely.
Why does it matter?
Respiratory distress is a medical emergency that can progress rapidly to respiratory failure (inability to breathe adequately) and death if not treated promptly. Early recognition and treatment (oxygen, treating the cause) are essential. The good news? With prompt treatment, most children recover completely.
Think of it like this: It's like your child struggling to breathe—they need urgent help, but with the right treatment, they usually recover quickly.
How is it treated?
1. Immediate Care (Most Important):
- Oxygen: Your child will get oxygen immediately to help them breathe
- Why: To support their breathing while we treat the cause
- Don't wait: Even before we know exactly what's causing it
2. Identify the Cause:
- Examination: Your doctor will examine your child to find out what's causing the breathing difficulty
- Tests: Your child may have tests (chest X-ray, etc.) if needed
- Why: To guide the right treatment
3. Treat the Cause:
- If asthma: Your child will get medicines to open the airways (bronchodilators) and reduce inflammation (steroids)
- If pneumonia: Your child will get antibiotics
- If bronchiolitis: Your child will get supportive care and oxygen
- If croup: Your child will get steroids
- If other causes: Treated as appropriate
4. Support Breathing (If Needed):
- If very severe: Your child may need help breathing (CPAP, BiPAP, or a breathing tube)
- Why: To support their breathing if they can't breathe well enough on their own
- When: If they're in respiratory failure or exhausted
The goal: Support your child's breathing (oxygen, ventilation if needed) and treat whatever's causing the breathing difficulty.
What to expect
Recovery:
- Most cases: Start improving within hours with treatment
- Symptoms: Should improve as the cause is treated
- Full recovery: Most children recover completely within days
After Treatment:
- Oxygen: Your child will continue to get oxygen until they can breathe well on their own
- Medications: Your child may need medications (depending on the cause)
- Monitoring: Close monitoring until your child is stable
- Going home: When your child is stable and breathing well
Recovery Time:
- Mild cases: Usually recover within hours
- Moderate cases: Usually recover within days
- Severe cases: May take longer, may need more support
When to seek help
Call 999 (or your emergency number) immediately if:
- Your child is having difficulty breathing
- Your child is breathing very fast
- Your child's skin is blue (cyanosis)
- Your child is very unwell
- Your child is exhausted from breathing
- You're very worried about your child
See your doctor if:
- Your child seems to be working hard to breathe
- Your child is breathing faster than normal
- Your child has symptoms that concern you
- You're worried about your child
Remember: If your child is having difficulty breathing, especially if they're breathing very fast, working hard to breathe, or their skin is blue, call 999 immediately. Respiratory distress is a medical emergency, but with prompt treatment, most children recover completely. Trust your instincts—if you're worried, seek help immediately.
Primary Guidelines
-
British Thoracic Society. British guideline on the management of asthma. BTS/SIGN. 2019.
-
National Institute for Health and Care Excellence. Bronchiolitis in children: diagnosis and management. NICE guideline [NG9]. 2015.
Key Trials
- Multiple studies on asthma treatment, oxygen use.
Further Resources
- BTS Guidelines: British Thoracic Society
- NICE Guidelines: National Institute for Health and Care Excellence
Last Reviewed: 2025-12-25 | MedVellum Editorial Team
Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists. This information is not a substitute for professional medical advice, diagnosis, or treatment.