Dog & Human Bites
Summary
Mammalian bites (Dog, Cat, Human) are common injuries with significant infection risk due to inoculation of oral flora deep into tissues. Dog bites are most common; Cat bites are small punctures but highly prone to infection; Human bites (especially the "Fight Bite" – Clenched fist injury over MCP joint) carry the worst prognosis due to joint penetration. Key organisms include Pasteurella multocida (Dogs/Cats), Capnocytophaga canimorsus (Dogs – Especially dangerous in Asplenic/Immunocompromised), and Eikenella corrodens (Human bites). Management includes thorough wound irrigation, appropriate antibiotic prophylaxis (Co-Amoxiclav is first-line), Tetanus prophylaxis, assessment for Rabies risk, and careful consideration of wound closure (Facial bites usually closed; Hand/puncture wounds often left open).
Key Facts
- Dog Bites: Most common. Crush injuries. Pasteurella. Capnocytophaga (Asplenic).
- Cat Bites: Deep punctures. High infection rate (30-50%). Pasteurella (Fast onset).
- Human Bites: "Fight Bite" = Clenched fist injury. Eikenella corrodens. High complication rate.
- Antibiotic: Co-Amoxiclav (Covers Pasteurella, Staph, Strep, Eikenella, Anaerobes).
- Closure: Facial bites – Close (Good blood supply). Hand/Puncture – Leave open or delayed closure.
- Tetanus: Booster if >10 years (or >5 years if dirty wound).
- Rabies: Assess risk (Animal source, Country, Vaccination status).
Clinical Pearls
"Fight Bite = Septic Arthritis Until Proven Otherwise": A wound over MCP in a clenched fist position likely penetrated the joint capsule. Treat aggressively.
"Cat Bites Infect Fast": Small punctures inoculate bacteria deep. Infection develops within 24 hours.
"Capnocytophaga in Asplenic Patients = Fulminant Sepsis": Dog bites in asplenic patients can cause rapid, fatal septicaemia.
"Co-Amoxiclav Covers Everything": First-line antibiotic for mammalian bites.
Why This Matters Clinically
Bites cause significant morbidity. Early recognition of high-risk wounds (Cat bites, Human fight bites, Immunocompromised host) and prompt antibiotic therapy prevent serious complications.
Incidence
- Dog Bites: ~60-90% of mammalian bites. ~250,000 A&E attendances/year (UK).
- Cat Bites: ~10-15%. Higher infection rate than dogs.
- Human Bites: ~3-5%. High complication rate.
Risk Factors for Infection
| Factor | Notes |
|---|---|
| Cat Bites | Puncture wounds. Deep inoculation. |
| Human Bites | Eikenella. Joint penetration. |
| Hand Bites | Poor blood supply. Tendon sheaths. Joint capsules. |
| Delayed Presentation (>2 hours) | |
| Immunocompromised | Diabetes, Steroids, Asplenia, HIV. |
| Puncture Wounds | Cannot be irrigated. |
| Crush Injuries | Devitalized tissue. |
Organisms by Bite Type
| Bite | Key Organisms |
|---|---|
| Dog | Pasteurella multocida, Pasteurella canis, Capnocytophaga canimorsus, Staphylococcus, Streptococcus, Anaerobes. |
| Cat | Pasteurella multocida (Most common, Rapid infection), Bartonella henselae (Cat Scratch Disease). |
| Human | Eikenella corrodens (Fastidious, Aggressive), Staphylococcus aureus, Streptococcus, Anaerobes, Viridans Streptococci. Sometimes Fusobacterium, Prevotella. |
Special Organisms
| Organism | Notes |
|---|---|
| Pasteurella multocida | Fast-growing. Cellulitis within 24 hours. Purulent discharge. |
| Eikenella corrodens | "Corrodes" agar. Aggressive. Associated with human bite/Fight Bite. |
| Capnocytophaga canimorsus | Dog/Cat saliva. Fulminant sepsis in Asplenic, Immunocompromised. DIC, Purpura Fulminans. High mortality. |
| Bartonella henselae | Cat Scratch Disease. Lymphadenopathy. |
Wound Types
| Type | Notes |
|---|---|
| Puncture | Cat bites. Small entry. Deep inoculation. |
| Laceration | Dog bites. Tearing. |
| Crush Injury | Dog bites. Devitalized tissue. |
| Avulsion | Tissue loss. Dog bites (Especially children). |
Signs of Infection
| Sign | Notes |
|---|---|
| Redness (Erythema) | Spreading. |
| Swelling | |
| Warmth | |
| Purulent Discharge | Yellow/Green pus. |
| Pain | Increasing. |
| Lymphangitis | Red streaking. |
| Systemic Signs | Fever. Malaise. (Sepsis). |
High-Risk Wounds
| Wound | Risk |
|---|---|
| Cat Bite (Any) | High infection rate. |
| Hand Bite | Joint/Tendon involvement. |
| Fight Bite (Clenched Fist) | MCP joint penetration. Septic arthritis. |
| Puncture Wounds | Cannot irrigate. |
| Delayed Presentation (>2-24 hours) | Already infected. |
| Immunocompromised Patient | Diabetes, Cirrhosis, Asplenia, Steroids. |
"Fight Bite" (Clenched Fist Injury)
| Feature | Notes |
|---|---|
| Mechanism | Punch to teeth. Wound over MCP (Dorsal). |
| Risk | Tooth penetrates joint capsule -> Septic arthritis. |
| Presentation | Wound appears minor. May present late with established infection. |
| Always X-Ray | Tooth fragment? |
| Management | Aggressive. Washout in theatre. IV Antibiotics. Often requires exploration. |
| Investigation | Purpose |
|---|---|
| X-Ray | Tooth fragments (Fight Bite). Fractures. Foreign body. Gas (Infection). |
| Wound Swab / Culture (If Infected) | Identify organism + Sensitivities. Request Pasteurella/Eikenella. |
| Bloods (If Systemic) | FBC, CRP, U&E. Blood cultures if septic. |
Principles
- History: Bite type (Dog, Cat, Human, Wild). Time since injury. Tetanus status. Allergies.
- Examination: Wound type. Depth. Neurovascular status. Tendon function. Joint involvement.
- Wound Care: Copious irrigation. Debride necrotic tissue.
- Antibiotics: Prophylaxis and/or Treatment.
- Tetanus Prophylaxis.
- Rabies Assessment.
- Wound Closure Decision.
- Referral if Indicated.
Wound Irrigation
- Copious Normal Saline (Or Tap Water).
- High Pressure (20-50ml syringe + Needle/Cannula).
- Aim for at least 250-500ml for significant wounds.
- Remove foreign material.
Antibiotic Therapy
First-Line: Co-Amoxiclav
| Drug | Dose | Duration | Notes |
|---|---|---|---|
| Co-Amoxiclav | 625mg TDS (Adults). | 5-7 days (Prophylaxis). 7-10 days (Treatment). | Covers Pasteurella, Eikenella, Staph, Strep, Anaerobes. |
If Penicillin Allergic
| Drug | Dose | Notes |
|---|---|---|
| Doxycycline | 100mg BD | + Metronidazole 400mg TDS. |
| Or Clarithromycin | 500mg BD | + Metronidazole 400mg TDS. |
Macrolides alone do NOT cover Pasteurella well.
Severe Infection / Sepsis
| Drug | Route | Notes |
|---|---|---|
| IV Co-Amoxiclav | 1.2g TDS | |
| Or IV Piperacillin-Tazobactam | Broad cover. | |
| Or Meropenem | If very severe/resistant. |
Tetanus Prophylaxis
| Vaccination History | Tetanus-Prone Wound (Bites) |
|---|---|
| Fully Vaccinated (5 doses), Last dose <10 years | No booster needed. |
| Fully Vaccinated, Last dose >0 years | Booster Td. |
| Not Fully Vaccinated / Unknown | Td vaccine + Tetanus Immunoglobulin (If dirty/high-risk). |
Rabies Assessment
| Question | Notes |
|---|---|
| Animal Type | Dog, Cat, Bat, Wild animal? |
| Animal Status | Known/Observable vs. Stray/Unknown? Vaccinated? |
| Country/Region | UK = Rabies-free (Low risk). Endemic regions = High risk. |
| Wound Type | Licks on broken skin. Bites. Scratches. |
| Pre-Exposure Vaccination | Previous rabies vaccination? |
If risk identified: Post-Exposure Prophylaxis (PEP) = Rabies vaccine +/- Rabies Immunoglobulin. Consult PHE/UKHSA.
Wound Closure
| Location / Type | Closure |
|---|---|
| Face | Primary closure (Good blood supply. Cosmetic importance). |
| Scalp | Usually close. |
| Hand / Puncture Wounds / Cat Bites | Leave open or Delayed Primary Closure (DPC). |
| Infected Wounds | Leave open. Dress. Review. |
| Large Wounds | May require surgical exploration + Delayed closure. |
Loose sutures if closing. Pack if leaving open. Follow-up essential.
Indications for Admission / Surgical Referral
| Indication | Action |
|---|---|
| Fight Bite (Over MCP) | Admit. IV Antibiotics. Theatre washout. |
| Tendon / Nerve / Joint Injury | Hand Surgery / Plastic Surgery. |
| Severe Infection / Abscess | Admit. IV Antibiotics. Incision & Drainage. |
| Sepsis / Immunocompromised | Admit. Blood Cultures. IV Antibiotics. |
| Complex Wounds / Tissue Loss | Plastics. |
| Complication | Notes |
|---|---|
| Cellulitis | Common. |
| Abscess | Requires drainage. |
| Septic Arthritis | Fight Bite. Cat bite to hand. Emergency. |
| Osteomyelitis | Deep infection. X-Ray/MRI. |
| Tenosynovitis | Hand bites. Kanavel's signs. |
| Sepsis / Septicaemia | Capnocytophaga (Asplenic). Pasteurella. Streptococcus. |
| Nerve Injury | Primary or Secondary to infection. |
| Tendon Damage | |
| Rabies | If applicable. Fatal if develops. |
| Scar / Cosmetic Deformity |
Asplenic / Hyposplenic Patients
| Risk | Notes |
|---|---|
| Capnocytophaga canimorsus | Fulminant sepsis. DIC. Purpura fulminans. |
| Management | Very low threshold for prophylactic antibiotics. Aggressive treatment. |
Immunocompromised (Diabetes, Cirrhosis, Steroids, HIV)
- Higher infection risk.
- Lower threshold for antibiotics.
Key Guidelines
| Guideline | Organisation | Notes |
|---|---|---|
| NICE CKS – Bites (Human and Animal) | NICE | UK primary care guidance. |
| PHE Rabies Guidelines | UKHSA/PHE | Post-Exposure Prophylaxis. |
Scenario 1:
- Stem: A man punched another person in the mouth. He presents with a wound over his right 4th MCP joint. What is the diagnosis and management?
- Answer: Fight Bite (Clenched Fist Injury). High risk of septic arthritis. X-Ray (Tooth fragment). Admit. IV Co-Amoxiclav. Washout in theatre.
Scenario 2:
- Stem: A woman is bitten on the hand by a cat. 12 hours later, she has swelling, redness, and purulent discharge. What organism is most likely?
- Answer: Pasteurella multocida (Rapid onset cellulitis from cat bite).
Scenario 3:
- Stem: What antibiotic is first-line for mammalian bite wounds?
- Answer: Co-Amoxiclav (Covers Pasteurella, Eikenella, Staph, Strep, Anaerobes).
| Scenario | Urgency | Action |
|---|---|---|
| Minor Bite, No Infection Risk | Routine | GP. Prophylactic antibiotics. Tetanus. |
| Infected Bite (Cellulitis) | Urgent | A&E / Urgent Review. Oral/IV Antibiotics. |
| Fight Bite / Hand Bite | Urgent | A&E. Hand Surgery referral. Theatre washout. |
| Tendon / Nerve / Joint Injury | Urgent | Hand Surgery / Plastics. |
| Sepsis / Severe Infection | Emergency | Admit. IV Antibiotics. Blood Cultures. |
| Rabies Risk (Travel History) | Urgent | PHE/UKHSA. PEP. |
What should I do if I'm bitten?
- Clean the wound: Wash thoroughly under running water for at least 5 minutes.
- Seek medical attention: Especially for cat bites, hand bites, or large wounds.
- Antibiotics: You may need a course to prevent infection.
- Tetanus: Make sure your vaccinations are up to date.
When should I worry?
- Wound getting redder, more swollen, or more painful.
- Pus or discharge.
- Fever or feeling unwell. Go back to the doctor or A&E if this happens.
Key Counselling Points
- Complete Antibiotic Course: "Finish all the antibiotics even if it looks better."
- Watch for Worsening Signs: "Come back if it gets redder, more swollen, or you feel unwell."
- Elevate Hand: "Keep your hand raised to reduce swelling."
| Standard | Target |
|---|---|
| Wound irrigation performed | 100% |
| Tetanus status assessed | 100% |
| Antibiotic prophylaxis given for high-risk bites | >5% |
| Fight Bite referred to Hand Surgery | 100% |
| Rabies risk assessed for travel/animal bite | 100% |
- Pasteurella first described late 19th Century. Named for Louis Pasteur.
- Capnocytophaga Sepsis: Increasingly recognised from 1970s. High mortality in asplenic patients.
- NICE CKS. Bites – Human and Animal. cks.nice.org.uk
- UKHSA. Rabies: PHE Guidelines on Post-Exposure Prophylaxis. gov.uk
Last Reviewed: 2025-12-24 | MedVellum Editorial Team
Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. If you have been bitten, seek medical attention.