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Dissociative Disorders

High EvidenceUpdated: 2025-12-22

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Red Flags

  • Often linked to severe childhood trauma
  • Self-harm or suicidality
  • Functional neurological symptoms
Overview

Dissociative Disorders

1. Clinical Overview

Summary

Dissociative disorders are a group of psychiatric conditions characterised by disruption in the normal integration of consciousness, memory, identity, emotion, perception, behaviour, or motor control. They are strongly associated with severe psychological trauma, particularly childhood abuse. The main disorders include Dissociative Identity Disorder (DID), Dissociative Amnesia, and Depersonalisation/Derealisation Disorder. Symptoms can be distressing and disabling. Treatment is primarily psychotherapy, especially trauma-focused approaches, with an emphasis on stabilisation, grounding, and gradual trauma processing.

Key Facts

  • DID (formerly Multiple Personality Disorder): Two or more distinct personality states
  • Dissociative Amnesia: Inability to recall important autobiographical information
  • Depersonalisation: Feeling detached from oneself (like an observer)
  • Derealisation: Feeling the world is unreal (like a dream)
  • Key Association: Childhood trauma/abuse
  • Treatment: Trauma-focused psychotherapy; Grounding techniques

Clinical Pearls

"Dissociation is a Defence": Dissociation develops as a protective mechanism against overwhelming trauma. Understanding this helps reduce stigma.

"Screen for Trauma": Dissociative symptoms often indicate underlying trauma. Sensitively screen for history of abuse.

"Grounding is Essential": Grounding techniques (e.g., 5-4-3-2-1 sensory exercise) are fundamental in managing acute dissociation.

"Rule Out Organic Causes": Always exclude epilepsy, substance use, and medical conditions that can cause dissociative-like symptoms.


2. Epidemiology

Prevalence

  • Dissociative symptoms: Common (10-15% of general population)
  • Dissociative disorders: 2-5%
  • DID: 1-1.5%

Demographics

  • F:M = 3:1 (DID)
  • Onset: Usually childhood/adolescence; often diagnosed in adulthood
  • Strong link with childhood trauma (90%+ of DID cases)

Risk Factors

FactorNotes
Childhood abusePhysical, sexual, emotional
NeglectEmotional neglect
Early traumaBefore age 9 particularly
Disorganised attachmentInconsistent caregiving
Lack of supportNo safe relationships

3. Pathophysiology

Trauma Model of Dissociation

  1. Overwhelming trauma (especially repeated, early, interpersonal)
  2. Dissociation as defence (escape when physical escape impossible)
  3. Failure of integration (memories, emotions, identity not consolidated)
  4. Structural dissociation (parts of personality hold trauma)

Neurobiological Findings

  • Hippocampal and prefrontal changes
  • HPA axis dysregulation
  • Altered connectivity between limbic and cortical areas

4. Clinical Presentation

Dissociative Identity Disorder (DID)

FeatureDescription
Multiple identity statesTwo or more distinct personality states
AmnesiaGaps in memory (between states)
Identity confusionUncertainty about identity
SwitchingTransition between states
Hearing voicesOften experienced as internal (unlike schizophrenia)

Dissociative Amnesia

FeatureDescription
Memory gapsCannot recall important autobiographical information (usually traumatic)
Usually reversibleUnlike organic amnesia
Dissociative fugueSudden travel away from home + amnesia

Depersonalisation/Derealisation Disorder

FeatureDescription
DepersonalisationFeeling detached from self (like watching oneself)
DerealisationWorld feels unreal (dreamlike, distant)
Reality testing intactKnows these experiences are not real
DistressingOften causes significant anxiety

Other Symptoms


Flashbacks, intrusive memories
Common presentation.
Unexplained physical symptoms (FNSD overlap)
Common presentation.
Emotional numbing
Common presentation.
Self-harm
Common presentation.
5. Clinical Examination

Mental State Examination

DomainPossible Findings
AppearanceMay change between presentations (DID)
BehaviourMay appear "absent," switching between states
SpeechMay change in tone/manner
MoodOften low, anxious
ThoughtConfusion about identity, intrusive trauma memories
PerceptionInternal voices (not true hallucinations)
CognitionAmnesia for periods of time
InsightVariable

Physical Examination

  • Exclude organic causes (epilepsy, substance use)
  • Look for self-harm

6. Investigations

Clinical Diagnosis

  • Primarily clinical (history and MSE)
  • Screening tools (DES - Dissociative Experiences Scale)

Exclude Organic Causes

TestExcludes
EEGEpilepsy (especially temporal lobe)
MRI brainStructural causes
Drug screenSubstance-induced dissociation
Thyroid functionMedical mimics

Psychological Assessment

  • Trauma history (sensitively explored)
  • DES (Dissociative Experiences Scale)
  • Structured interviews (SCID-D)

7. Management

Treatment Approach

┌──────────────────────────────────────────────────────────┐
│   DISSOCIATIVE DISORDERS MANAGEMENT                      │
├──────────────────────────────────────────────────────────┤
│                                                          │
│  PHASE 1: STABILISATION & SAFETY                          │
│  • Build therapeutic alliance                            │
│  • Teach grounding techniques                            │
│  • Establish safety (self-harm, suicidality)             │
│  • Psychoeducation about dissociation                    │
│  • Develop coping skills                                 │
│                                                          │
│  PHASE 2: TRAUMA PROCESSING (When stable)                 │
│  • Trauma-focused CBT                                    │
│  • EMDR (Eye Movement Desensitisation & Reprocessing)    │
│  • Gradual exposure to trauma memories                   │
│  • Schema therapy                                        │
│                                                          │
│  PHASE 3: INTEGRATION & RECONNECTION                      │
│  • Identity integration (DID)                            │
│  • Building meaningful relationships                     │
│  • Life goals and functioning                            │
│                                                          │
│  MEDICATION (Adjunctive; targets symptoms):               │
│  • SSRIs (for depression, anxiety)                       │
│  • No specific medication for dissociation               │
│  • Avoid benzodiazepines (worsen dissociation)           │
│                                                          │
│  GROUNDING TECHNIQUES:                                    │
│  • 5-4-3-2-1 (5 things you see, 4 hear, 3 touch...)      │
│  • Cold water on hands/face                              │
│  • Describe surroundings out loud                        │
│  • Smell strong scent (coffee, peppermint)               │
│                                                          │
└──────────────────────────────────────────────────────────┘

8. Complications

Of Disorder

  • Self-harm and suicide
  • Impaired functioning (work, relationships)
  • Comorbid PTSD, depression, anxiety
  • Substance misuse
  • Somatisation

Of Treatment

  • Re-traumatisation (if trauma processing too early)
  • Therapeutic dependency

9. Prognosis & Outcomes

With Treatment

  • Significant improvement possible
  • DID integration or functional coexistence
  • Long-term therapy often needed

Without Treatment

  • Chronic symptoms
  • Recurrent crises
  • Ongoing functional impairment

10. Evidence & Guidelines

Key Guidelines

  1. ISSTD: Treatment Guidelines for Dissociative Identity Disorder
  2. NICE: PTSD Guidelines (overlapping principles)

Key Evidence

Psychotherapy

  • Phase-oriented trauma therapy is evidence-based
  • EMDR and trauma-focused CBT effective

11. Patient/Layperson Explanation

What Are Dissociative Disorders?

Dissociative disorders are mental health conditions where you feel disconnected from your thoughts, feelings, surroundings, or sense of identity. They often develop as a way of coping with overwhelming experiences, especially trauma.

What Are the Types?

  • Dissociative Identity Disorder: Having two or more distinct personality states
  • Dissociative Amnesia: Not being able to remember important things about yourself
  • Depersonalisation: Feeling like you're watching yourself from outside your body
  • Derealisation: Feeling like the world isn't real

What Causes It?

Usually, dissociative disorders develop after severe or repeated trauma, especially in childhood. The mind learns to "disconnect" as a way to cope.

How is it Treated?

  • Therapy is the main treatment - especially trauma-focused therapy
  • Grounding techniques help you stay present when you feel disconnected
  • Medication may help with symptoms like depression or anxiety

Is Recovery Possible?

Yes. With the right support and therapy, many people with dissociative disorders lead full and meaningful lives.


12. References

Primary Guidelines

  1. International Society for the Study of Trauma and Dissociation. Guidelines for Treating Dissociative Identity Disorder in Adults. J Trauma Dissociation. 2011.

Key Studies

  1. Brand BL, et al. A longitudinal naturalistic study of patients with dissociative disorders. Psychol Trauma. 2013. PMID: 23914751

Last updated: 2025-12-22

At a Glance

EvidenceHigh
Last Updated2025-12-22

Red Flags

  • Often linked to severe childhood trauma
  • Self-harm or suicidality
  • Functional neurological symptoms

Clinical Pearls

  • **"Dissociation is a Defence"**: Dissociation develops as a protective mechanism against overwhelming trauma. Understanding this helps reduce stigma.
  • **"Screen for Trauma"**: Dissociative symptoms often indicate underlying trauma. Sensitively screen for history of abuse.
  • **"Grounding is Essential"**: Grounding techniques (e.g., 5-4-3-2-1 sensory exercise) are fundamental in managing acute dissociation.
  • **"Rule Out Organic Causes"**: Always exclude epilepsy, substance use, and medical conditions that can cause dissociative-like symptoms.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines