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Acute Dehydration - Paediatric

High EvidenceUpdated: 2025-12-25

On This Page

Red Flags

  • Severe dehydration
  • Shock
  • Altered mental status
  • Signs of severe fluid loss
  • Unable to take oral fluids
  • Signs of electrolyte imbalance
Overview

Acute Dehydration - Paediatric

1. Clinical Overview

Summary

Acute dehydration in children occurs when the body loses more fluid than it takes in, leading to a deficit in total body water. Think of your child's body as needing a constant supply of water to function—when fluid losses (from vomiting, diarrhea, fever, reduced intake) exceed fluid intake, the body becomes dehydrated, affecting all organ systems. Dehydration is very common in children, especially infants and young children, who have a higher proportion of body water and are more vulnerable to fluid losses. The most common causes are gastroenteritis (vomiting and diarrhea), fever, and reduced fluid intake. The severity ranges from mild (minimal symptoms) to severe (shock, organ failure). The key to management is recognizing the severity (using clinical signs—skin turgor, capillary refill, mucous membranes, fontanelle in infants, eyes), providing appropriate rehydration (oral rehydration solution for mild-moderate, IV fluids for severe or unable to take oral), treating the underlying cause, and monitoring for complications. Most children recover well with appropriate rehydration, but severe dehydration can be life-threatening if not treated promptly.

Key Facts

  • Definition: Deficit in total body water due to losses exceeding intake
  • Incidence: Very common (millions of cases/year worldwide)
  • Mortality: Very low (<0.1%) unless severe and untreated
  • Peak age: Infants and young children (highest risk)
  • Critical feature: Fluid losses exceeding intake, clinical signs of dehydration
  • Key investigation: Clinical assessment (usually sufficient)
  • First-line treatment: Oral rehydration (mild-moderate), IV fluids (severe or unable to take oral)

Clinical Pearls

"Clinical assessment is key" — The severity of dehydration is assessed clinically (skin turgor, capillary refill, mucous membranes, fontanelle, eyes). Don't rely on weight alone—clinical signs are more important.

"Oral rehydration works for most" — Most children with mild-moderate dehydration can be rehydrated orally with oral rehydration solution (ORS). IV fluids are only needed for severe dehydration or if unable to take oral fluids.

"Infants are more vulnerable" — Infants have a higher proportion of body water and are more vulnerable to dehydration. Have a lower threshold for concern in infants.

"Treat the cause" — Always treat the underlying cause (gastroenteritis, fever, etc.) while rehydrating. Rehydration alone isn't enough if the cause isn't addressed.

Why This Matters Clinically

Dehydration is very common in children and can be life-threatening if severe and not treated promptly. Early recognition (especially in infants where signs may be subtle), appropriate rehydration (oral for most, IV for severe), and treating the underlying cause are essential. This is a condition that all clinicians caring for children need to recognize and manage, as it's very common and usually easily treated.


2. Epidemiology

Incidence & Prevalence

  • Overall: Very common (millions of cases/year worldwide)
  • Trend: Stable (common condition)
  • Peak age: Infants and young children (highest risk)

Demographics

FactorDetails
AgeHighest risk in infants and young children (<5 years)
SexNo significant variation
EthnicityHigher in resource-poor settings
GeographyMuch higher in developing countries
SettingEmergency departments, general practice, pediatric clinics

Risk Factors

Non-Modifiable:

  • Age (infants and young children = highest risk)
  • Prematurity (higher risk)

Modifiable:

Risk FactorRelative RiskMechanism
Gastroenteritis10-20xVomiting, diarrhea
Fever3-5xIncreased fluid losses
Reduced intake3-5xNot drinking enough
Hot weather2-3xIncreased fluid losses
Poor access to clean water2-3xIn developing countries

Common Causes

CauseFrequencyTypical Patient
Gastroenteritis60-70%Vomiting, diarrhea
Fever10-15%High fever, reduced intake
Reduced intake10-15%Not drinking, illness
Other10-15%Various

3. Pathophysiology

The Dehydration Mechanism

Step 1: Fluid Losses Exceed Intake

  • Losses: Vomiting, diarrhea, fever, sweating, reduced intake
  • Intake: Reduced fluid intake
  • Result: Negative fluid balance

Step 2: Body Water Deficit

  • Total body water: Decreases
  • Blood volume: Decreases
  • Result: Dehydration

Step 3: Compensatory Mechanisms

  • Thirst: Increases (if able)
  • ADH: Increases (retains water)
  • Aldosterone: Increases (retains sodium)
  • Result: Body tries to conserve water

Step 4: Clinical Manifestation

  • Mild: Minimal symptoms
  • Moderate: More obvious signs
  • Severe: Shock, organ dysfunction
  • Result: Signs of dehydration

Step 5: Recovery or Progression

  • With rehydration: Recovers
  • Without rehydration: Progresses to shock
  • Result: Depends on treatment

Classification by Severity

SeverityFluid DeficitClinical Features
Mild3-5%Minimal signs, good function
Moderate5-10%Obvious signs, some dysfunction
Severe>10%Severe signs, shock, organ dysfunction

Anatomical Considerations

Body Water Distribution:

  • Infants: Higher proportion of body water (75-80%)
  • Children: Lower proportion (60-65%)
  • Adults: Lower proportion (50-60%)

Why Infants are Vulnerable:

  • Higher proportion: More body water to lose
  • Higher metabolic rate: More fluid losses
  • Less ability to communicate: Can't say they're thirsty
  • Smaller reserves: Less ability to compensate

4. Clinical Presentation

Symptoms: The Patient's Story

Typical Presentation:

Mild Dehydration:

Moderate Dehydration:

Severe Dehydration:

Signs: What You See

Vital Signs (May Be Abnormal):

SignFindingSignificance
TemperatureMay be elevated (if fever)Fever
Heart rateMay be high (compensatory, shock)Tachycardia
Blood pressureMay be low (if severe)Hypotension, shock
Respiratory rateUsually normal (may be high if severe)Usually normal

General Appearance:

Clinical Signs of Dehydration:

FindingWhat It MeansFrequency
Reduced skin turgorPoor skin elasticity60-70%
Slow capillary refillPoor perfusion (>2 seconds)50-60%
Dry mucous membranesDry mouth, no tears70-80%
Sunken eyesReduced eye fluid40-50%
Sunken fontanelleReduced intracranial fluid (infants)50-60% (infants)
Reduced urine outputDecreased urineCommon

Signs by Severity:

SeveritySigns
MildSlightly dry mouth, normal skin turgor
ModerateDry mouth, reduced skin turgor, sunken eyes, reduced urine
SevereVery dry mouth, very reduced skin turgor, sunken eyes, sunken fontanelle, shock, altered mental status

Red Flags

[!CAUTION] Red Flags — Immediate Escalation Required:

  • Severe dehydration — Medical emergency, needs urgent IV fluids
  • Shock — Medical emergency, needs urgent resuscitation
  • Altered mental status — Medical emergency, needs urgent assessment
  • Signs of severe fluid loss — Needs urgent treatment
  • Unable to take oral fluids — Needs IV fluids
  • Signs of electrolyte imbalance — Needs assessment, may need correction

Reduced intake
Not drinking well
Increased losses
Vomiting, diarrhea, fever
Symptoms
Vary by severity
5. Clinical Examination

Structured Approach: ABCDE

A - Airway

  • Assessment: Usually patent
  • Action: Secure if compromised

B - Breathing

  • Look: Usually normal (may have tachypnea if severe)
  • Listen: Usually normal
  • Measure: SpO2 (usually normal)
  • Action: Support if needed

C - Circulation

  • Look: Poor perfusion (mottled, cold), signs of shock
  • Feel: Pulse (may be fast, weak), BP (may be low), capillary refill (slow)
  • Listen: Heart sounds (usually normal)
  • Measure: BP (may be low), HR (may be high)
  • Action: IV fluids urgently if severe

D - Disability

  • Assessment: Mental status (may be altered if severe)
  • Action: Assess if severe

E - Exposure

  • Look: Full examination, assess dehydration signs
  • Feel: Skin turgor, fontanelle (infants)
  • Action: Complete examination, assess severity

Specific Examination Findings

Dehydration Assessment (Critical):

SignTechniqueFindingClinical Use
Skin turgorPinch skin on abdomenSlow return (>2 seconds)Moderate-severe dehydration
Capillary refillPress nail bed, release>2 secondsPoor perfusion
Mucous membranesCheck mouthDryDehydration
EyesCheck eyesSunkenModerate-severe dehydration
FontanelleCheck fontanelle (infants)SunkenModerate-severe dehydration
TearsCheck for tearsAbsentModerate-severe dehydration

Weight (If Available):

  • Comparison: Compare to recent weight
  • Loss: Weight loss indicates fluid deficit
  • Action: Helps assess severity

Special Tests

TestTechniquePositive FindingClinical Use
Skin turgorPinch skinSlow returnAssesses dehydration
Capillary refillPress nail bed>2 secondsAssesses perfusion
FontanelleCheck fontanelleSunkenAssesses dehydration (infants)

6. Investigations

First-Line (Bedside) - Do Immediately

1. Clinical Assessment (Most Important)

  • Signs: Skin turgor, capillary refill, mucous membranes, eyes, fontanelle
  • Action: Usually sufficient for diagnosis and severity assessment

2. Weight (If Available)

  • Comparison: Compare to recent weight
  • Action: Helps assess severity

Laboratory Tests

TestExpected FindingPurpose
Urea & ElectrolytesMay show elevated urea, electrolyte imbalancesAssesses severity, electrolyte status
Full Blood CountMay show hemoconcentration (high hematocrit)Assesses severity
GlucoseMay be low (if severe)Assesses for hypoglycemia

Imaging

Usually not needed — Clinical assessment is usually sufficient.

Diagnostic Criteria

Clinical Diagnosis:

  • History of fluid losses (vomiting, diarrhea, fever, reduced intake) + clinical signs of dehydration = Dehydration

Severity Assessment:

  • Mild (3-5%): Slightly dry mouth, normal skin turgor
  • Moderate (5-10%): Dry mouth, reduced skin turgor, sunken eyes, reduced urine
  • Severe (>10%): Very dry mouth, very reduced skin turgor, sunken eyes, sunken fontanelle, shock, altered mental status

7. Management

Management Algorithm

        SUSPECTED DEHYDRATION (CHILD)
    (Fluid losses + signs of dehydration)
                    ↓
┌─────────────────────────────────────────────────┐
│         ASSESS SEVERITY                          │
│  • Clinical signs (skin turgor, capillary refill) │
│  • Weight (if available)                          │
│  • Classify: mild, moderate, severe                │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         TREATMENT                                │
├─────────────────────────────────────────────────┤
│  MILD (3-5%)                                    │
│  → Oral rehydration solution (ORS)               │
│  → Encourage fluids                              │
│  → Treat underlying cause                         │
│                                                  │
│  MODERATE (5-10%)                               │
│  → Oral rehydration solution (ORS)               │
│  → If unable to take oral: IV fluids             │
│  → Treat underlying cause                         │
│                                                  │
│  SEVERE (&gt;10%)                                  │
│  → IV fluids urgently                             │
│  → Resuscitation if shock                        │
│  → Treat underlying cause                         │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         ORAL REHYDRATION (IF MILD-MODERATE)      │
│  • Oral rehydration solution (ORS)                 │
│  • Small, frequent sips                           │
│  • Continue until rehydrated                       │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         IV FLUIDS (IF SEVERE OR UNABLE TO TAKE ORAL) │
│  • IV access (urgent)                             │
│  • IV fluids (normal saline or Hartmann's)         │
│  • 20ml/kg bolus if shock, then maintenance        │
│  • Monitor closely                                 │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         TREAT UNDERLYING CAUSE                    │
│  • Gastroenteritis: Supportive care                │
│  • Fever: Treat fever                              │
│  • Other: As appropriate                            │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         MONITOR & FOLLOW-UP                        │
│  • Monitor for improvement                         │
│  • Reassess severity                                │
│  • Discharge when stable                            │
└─────────────────────────────────────────────────┘

Acute/Emergency Management - The First Hour

Immediate Actions (Do Simultaneously):

  1. Assess Severity

    • Clinical signs: Skin turgor, capillary refill, mucous membranes, eyes, fontanelle
    • Weight: If available, compare to recent
    • Action: Classify as mild, moderate, or severe
  2. Oral Rehydration (If Mild-Moderate and Able to Take Oral)

    • ORS: Oral rehydration solution
    • Small, frequent sips: Don't force large amounts
    • Action: Rehydrate orally
  3. IV Fluids (If Severe or Unable to Take Oral)

    • IV access: Establish urgently
    • IV fluids: Normal saline or Hartmann's
    • Bolus: 20ml/kg if shock, then maintenance
    • Action: Rehydrate urgently
  4. Treat Underlying Cause

    • Gastroenteritis: Supportive care
    • Fever: Paracetamol/ibuprofen
    • Other: As appropriate
    • Action: Address cause
  5. Monitor

    • Reassess: Reassess severity
    • Monitor: Close monitoring
    • Action: Ensure improvement

Medical Management

Oral Rehydration Solution (ORS):

SolutionIndicationNotes
ORSMild-moderate dehydrationStandard ORS solution
Small, frequent sipsDon't force large amountsPrevents vomiting

IV Fluids (If Severe or Unable to Take Oral):

FluidDoseRouteNotes
Normal saline20ml/kg bolus (if shock), then maintenanceIVFirst-line
Hartmann's20ml/kg bolus (if shock), then maintenanceIVAlternative

Maintenance Fluids:

  • Calculate: Based on weight (100ml/kg/day for first 10kg, 50ml/kg/day for next 10kg, 20ml/kg/day for remainder)
  • Plus deficit: Add deficit replacement
  • Action: Maintain hydration

Disposition

Admit to Hospital If:

  • Severe dehydration: Needs IV fluids, monitoring
  • Unable to take oral: Needs IV fluids
  • Shock: Needs resuscitation, ICU

Outpatient Management:

  • Mild-moderate: Can be managed outpatient if able to take oral
  • Regular follow-up: Monitor improvement

Discharge Criteria:

  • Stable: No complications
  • Able to take oral: Taking fluids well
  • Improving: Signs of improvement
  • Clear plan: For continued rehydration, follow-up

Follow-Up:

  • Most recover: With appropriate rehydration
  • If gastroenteritis: Usually resolves
  • Long-term: Usually no long-term issues

8. Complications

Immediate (Hours-Days)

ComplicationIncidencePresentationManagement
Shock5-10% (if severe)Hypotension, poor perfusionIV fluids, resuscitation
Electrolyte imbalances10-20%Varies by imbalanceCorrect electrolytes
Hypoglycemia5-10% (if severe)Low blood sugarIV glucose
Acute kidney injury5-10% (if severe)Reduced urine outputSupportive care, may need dialysis

Shock:

  • Mechanism: Severe fluid deficit
  • Management: IV fluids, resuscitation
  • Prevention: Early recognition, treatment

Early (Days-Weeks)

1. Usually Full Recovery (90-95%)

  • Mechanism: Most recover with rehydration
  • Management: Usually no long-term treatment needed
  • Prevention: Early treatment

2. Persistent Issues (5-10%)

  • Mechanism: If underlying cause persists
  • Management: Treat underlying cause
  • Prevention: Address underlying cause

Late (Months-Years)

1. Usually No Long-Term Issues (95%+)

  • Mechanism: Most recover completely
  • Management: Usually no long-term treatment needed
  • Prevention: N/A

9. Prognosis & Outcomes

Natural History (Without Treatment)

Untreated Dehydration:

  • Mild: Usually resolves (if able to drink)
  • Moderate: May progress to severe
  • Severe: High risk of shock, organ failure, death

Outcomes with Treatment

VariableOutcomeNotes
Recovery95-98%Most recover with appropriate rehydration
Mortality<0.1%Very low with prompt treatment
Time to recoveryHours to daysWith treatment

Factors Affecting Outcomes:

Good Prognosis:

  • Early treatment: Better outcomes
  • Mild-moderate: Usually recover quickly
  • Able to take oral: Usually recover quickly
  • No complications: Better outcomes

Poor Prognosis:

  • Delayed treatment: Higher risk of complications
  • Severe dehydration: Longer recovery, more complications
  • Shock: More serious, needs ICU
  • Very young: May have worse outcomes

Prognostic Factors

FactorImpact on PrognosisEvidence Level
Early treatmentBetter outcomesHigh
SeverityMore severe = worseHigh
AgeVery young = worseModerate
Underlying causeSome causes worseModerate

10. Evidence & Guidelines

Key Guidelines

1. WHO Guidelines (2005) — The treatment of diarrhoea: a manual for physicians and other senior health workers. World Health Organization

Key Recommendations:

  • Oral rehydration for mild-moderate
  • IV fluids for severe
  • Evidence Level: 1A

2. NICE Guidelines (2009) — Diarrhoea and vomiting caused by gastroenteritis: diagnosis, assessment and management in children younger than 5 years. National Institute for Health and Care Excellence

Key Recommendations:

  • Similar to WHO
  • Evidence Level: 1A

Landmark Trials

Multiple studies on oral rehydration, IV fluids.

Evidence Strength

InterventionLevelKey EvidenceClinical Recommendation
Oral rehydration1AMultiple RCTsFirst-line for mild-moderate
IV fluids1AMultiple studiesEssential for severe

11. Patient/Layperson Explanation

What is Dehydration?

Dehydration happens when your child's body loses more fluid than it takes in, leading to a deficit in total body water. Think of your child's body as needing a constant supply of water to function—when fluid losses (from vomiting, diarrhea, fever, or not drinking enough) exceed fluid intake, the body becomes dehydrated.

In simple terms: Your child's body doesn't have enough water. This is usually easy to fix by giving your child fluids, but if severe, it can be serious and needs urgent treatment.

Why does it matter?

Dehydration is very common in children and can be serious if severe and not treated. Early recognition and appropriate rehydration (giving fluids) are essential. The good news? Most children recover quickly with appropriate rehydration.

Think of it like this: It's like your child's body running low on water—with the right fluids, it usually recovers quickly.

How is it treated?

1. Assess How Severe:

  • Your doctor will check: Your child's skin, mouth, eyes, and other signs to see how dehydrated they are
  • Why: To decide the best way to rehydrate

2. Give Fluids:

  • If mild-moderate: Your child will drink special rehydration solution (ORS) - small, frequent sips
  • If severe or can't drink: Your child will get fluids through a drip (IV fluids)
  • Why: To replace the lost fluid

3. Treat the Cause:

  • If gastroenteritis: Supportive care
  • If fever: Medicine to reduce fever
  • If other causes: Treated as appropriate
  • Why: To stop the fluid losses

4. Monitor:

  • Your doctor will watch: To make sure your child is improving
  • Reassess: To see if more treatment is needed

The goal: Replace the lost fluid and treat whatever's causing the fluid losses.

What to expect

Recovery:

  • Mild cases: Usually recover within hours with oral fluids
  • Moderate cases: Usually recover within hours to a day with oral or IV fluids
  • Severe cases: Usually recover within days with IV fluids

After Treatment:

  • Fluids: Your child will continue to need fluids (oral or IV) until rehydrated
  • Monitoring: Your doctor will monitor to make sure your child is improving
  • Going home: When your child is stable and able to take fluids

Recovery Time:

  • Mild cases: Usually hours
  • Moderate cases: Usually hours to a day
  • Severe cases: Usually days

When to seek help

See your doctor if:

  • Your child is not drinking well
  • Your child has vomiting or diarrhea and seems dehydrated
  • Your child has a fever and seems dehydrated
  • Your child's mouth is dry, or they're not making tears
  • You're concerned about your child

Call 999 (or your emergency number) immediately if:

  • Your child is very unwell
  • Your child is confused or not responding normally
  • Your child's skin is mottled or cold
  • Your child is in shock
  • You're very worried about your child

Remember: If your child is not drinking well, especially if they have vomiting, diarrhea, or a fever, see your doctor. Dehydration is usually easy to fix, but if severe, it needs urgent treatment. Trust your instincts—if you're worried, seek help.


12. References

Primary Guidelines

  1. World Health Organization. The treatment of diarrhoea: a manual for physicians and other senior health workers. WHO. 2005.

  2. National Institute for Health and Care Excellence. Diarrhoea and vomiting caused by gastroenteritis: diagnosis, assessment and management in children younger than 5 years. NICE guideline [CG84]. 2009.

Key Trials

  1. Multiple studies on oral rehydration and IV fluids.

Further Resources

  • WHO Guidelines: World Health Organization
  • NICE Guidelines: National Institute for Health and Care Excellence

Last Reviewed: 2025-12-25 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists. This information is not a substitute for professional medical advice, diagnosis, or treatment.

Last updated: 2025-12-25

At a Glance

EvidenceHigh
Last Updated2025-12-25

Red Flags

  • Severe dehydration
  • Shock
  • Altered mental status
  • Signs of severe fluid loss
  • Unable to take oral fluids
  • Signs of electrolyte imbalance

Clinical Pearls

  • **"Infants are more vulnerable"** — Infants have a higher proportion of body water and are more vulnerable to dehydration. Have a lower threshold for concern in infants.
  • **"Treat the cause"** — Always treat the underlying cause (gastroenteritis, fever, etc.) while rehydrating. Rehydration alone isn't enough if the cause isn't addressed.
  • **Red Flags — Immediate Escalation Required:**
  • - **Severe dehydration** — Medical emergency, needs urgent IV fluids
  • - **Shock** — Medical emergency, needs urgent resuscitation

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines