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Psychiatry
Paediatrics
Child and Adolescent Psychiatry

Conduct Disorder

High EvidenceUpdated: 2025-12-24

On This Page

Red Flags

  • Precursor to Antisocial Personality Disorder
  • Callous-unemotional traits (poor prognosis)
  • History of cruelty to animals or fire-setting
  • Comorbid substance misuse
  • Risk of harm to self or others
Overview

Conduct Disorder

1. Clinical Overview

Summary

Conduct disorder (CD) is a childhood-onset psychiatric condition characterised by a repetitive and persistent pattern of behaviour that violates the basic rights of others or major age-appropriate societal norms and rules. Core features include aggression towards people and animals, destruction of property, deceitfulness or theft, and serious violations of rules. It is closely related to Oppositional Defiant Disorder (ODD), which is often considered a less severe precursor. CD is a significant risk factor for the development of Antisocial Personality Disorder (ASPD) in adulthood. The presence of callous-unemotional (CU) traits (lack of guilt, reduced empathy) indicates a more severe subtype with poorer prognosis. Management is primarily psychological, focusing on parent training programmes, multi-systemic therapy (MST), and addressing comorbidities.

Key Facts

  • Prevalence: 3-5% of children; higher in boys (3:1 ratio)
  • Onset: Childhood-onset (<10 years) has worse prognosis than adolescent-onset
  • ODD vs CD: ODD is less severe (no aggression to people/animals, no destruction of property); CD is more severe
  • Callous-Unemotional (CU) traits: Lack of guilt/remorse; poor empathy; poor prognosis; DSM-5 specifier
  • Progression: ODD → CD → Antisocial Personality Disorder (pathway, not inevitable)
  • Comorbidities: ADHD (~50%), substance misuse, depression, learning difficulties
  • Management: Parent training (e.g., Webster-Stratton), Multi-Systemic Therapy (MST)
  • Prognosis: Childhood-onset with CU traits has worst outcome; adolescent-onset often improves

Clinical Pearls

"The Triad of Fire-Setting, Bedwetting, Cruelty to Animals": Historically called the MacDonald triad, these behaviours in childhood were thought to predict violent behaviour. While not diagnostic, cruelty to animals and fire-setting are serious warning signs requiring urgent assessment.

"ODD Is Not Just a Naughty Child": ODD involves a pattern of angry, irritable mood and defiant behaviour lasting at least 6 months. It is a clinical diagnosis, not just normal childhood misbehaviour.

"Callous-Unemotional = High Risk": Children with CU traits (lack of guilt, shallow affect, unconcern about performance, reduced empathy) have poorer response to treatment and are at higher risk of adult antisocial behaviour.

"Parent Training First": NICE recommends parent training programmes as first-line for children under 12. These focus on positive parenting strategies, limit-setting, and improving the parent-child relationship.

"Multi-Systemic Therapy for Severe Cases": MST is an evidence-based intensive family and community-based treatment for adolescents with severe conduct problems. It addresses family, peer, school, and community factors.

Why This Matters Clinically

Conduct disorder is one of the most common reasons for child and adolescent mental health referral. Early identification and intervention can alter the trajectory towards ASPD and reduce long-term criminal justice involvement, substance misuse, and mental health problems. Recognising comorbidities (especially ADHD) and the presence of CU traits is essential for appropriate management and prognostication.[1,2]


2. Epidemiology

Incidence & Prevalence

ParameterData
Prevalence3-5% of school-age children
Sex ratioMale:Female = 3:1 (boys more aggressive; girls more covert)
OnsetChildhood-onset (<10 years) or adolescent-onset (>10 years)
Progression to ASPD~40% of childhood-onset CD develop ASPD; lower for adolescent-onset

Risk Factors

FactorNotes
GeneticHeritability ~50%; gene-environment interaction
Family environmentHarsh/inconsistent parenting, abuse, neglect
Parental psychopathologyParental antisocial behaviour, substance misuse, depression
SocioeconomicPoverty, inner-city living
Peer influencesDeviant peer groups
School factorsExclusion, learning difficulties
TemperamentDifficult temperament; impulsivity

Relationship Between ODD, CD, and ASPD

DiagnosisAgeKey Features
ODDChildrenAngry/irritable mood; defiant/argumentative; vindictive
CDChildren/AdolescentsAggression, destruction, deceit, rule violations
ASPDAdults (≥18)Pervasive disregard for rights of others; requires CD before 15

3. Pathophysiology

Neurobiological Factors

FactorEvidence
Prefrontal cortex dysfunctionReduced activity in areas involved in impulse control and decision-making
Amygdala abnormalitiesReduced amygdala reactivity to fear and distress cues (especially CU traits)
Low cortisolReduced stress response; less sensitivity to punishment
Serotonin dysregulationAssociated with impulsivity and aggression
Autonomic underarousalLow heart rate at rest; reduced fear response

Developmental Pathway

Step 1: Temperament and Early Environment

  • Difficult temperament (impulsivity, negative emotionality)
  • Adverse early environment (harsh parenting, abuse, neglect)

Step 2: Coercive Family Processes

  • Negative parent-child interactions escalate
  • Child learns that aggression/defiance leads to parental capitulation
  • Positive behaviours not reinforced

Step 3: ODD Emergence

  • Angry, defiant behaviours become established
  • Pattern of oppositional behaviour

Step 4: CD Development

  • Escalation to more severe behaviours (aggression, rule violations)
  • Association with deviant peers
  • School difficulties and exclusion

Step 5: Adult Trajectory

  • Without intervention: high risk of ASPD, criminal activity, substance misuse
  • With intervention: improved outcomes possible

Callous-Unemotional (CU) Traits

FeatureDescription
Lack of remorse/guiltAbsence of guilt after wrongdoing
Callous/lack of empathyDisregard for others' feelings
Unconcerned about performanceIndifference to poor school/work performance
Shallow/deficient affectLimited emotional expression; uses emotions manipulatively

4. Clinical Presentation

DSM-5 Diagnostic Criteria for Conduct Disorder

A. Repetitive and persistent pattern of behaviour violating rights of others or societal norms:

At least 3 of the following in the past 12 months (at least 1 in past 6 months):

Aggression to People and Animals:

  1. Often bullies, threatens, or intimidates others
  2. Often initiates physical fights
  3. Has used a weapon that can cause serious physical harm
  4. Has been physically cruel to people
  5. Has been physically cruel to animals
  6. Has stolen while confronting a victim (mugging, armed robbery)
  7. Has forced someone into sexual activity

Destruction of Property: 8. Has deliberately engaged in fire-setting with intention to cause damage 9. Has deliberately destroyed others' property

Deceitfulness or Theft: 10. Has broken into someone's house, building, or car 11. Often lies to obtain goods or favours or to avoid obligations 12. Has stolen items of non-trivial value without confrontation (shoplifting)

Serious Violations of Rules: 13. Often stays out at night despite parental prohibitions (before age 13) 14. Has run away from home overnight at least twice 15. Is often truant from school (before age 13)

B. Causes clinically significant impairment in social, academic, or occupational functioning.

C. If ≥18 years, criteria for ASPD are not met.

ODD vs CD Symptoms

ODDCD
Angry/irritable moodAggression to people/animals
Argumentative/defiant behaviourDestruction of property
Vindictive behaviourDeceitfulness/theft
—Serious rule violations

Red Flags

[!CAUTION] Red Flags — Urgent Assessment:

  • Cruelty to animals (marker of severity)
  • Fire-setting with intent to harm
  • Use of weapons
  • Sexual aggression
  • Expressed intent to harm others
  • Suicidal ideation (comorbidity)
  • Substance misuse

5. Clinical Examination

Mental State Examination (MSE)

DomainPossible Findings
AppearanceMay be guarded, hostile, or dismissive
BehaviourMay be oppositional; difficulty with authority
SpeechMay be monosyllabic, evasive, or challenging
MoodOften describes as "fine"; may report anger/irritability
AffectMay be restricted; shallow in CU traits
Thought contentExternalises blame; may minimise behaviour
CognitionAssess for comorbid learning difficulties
InsightOften poor; may not see behaviour as problematic
RiskAssess risk to self and others; substance misuse

Assessment Domains

DomainQuestions/Areas
Behaviour historySpecific incidents; onset; frequency; severity
Family functioningParenting style; parental mental health; family conflict
SchoolAttainment; exclusions; relationships with teachers/peers
Peer relationshipsDeviant peers; bullying (perpetrator or victim)
Substance misuseAlcohol; drugs; pattern of use
Trauma historyAbuse; neglect; witnessed violence
ComorbiditiesADHD; depression; anxiety; learning difficulties

6. Investigations

Purpose

No diagnostic blood test or imaging. Investigations are to:

  1. Assess for comorbidities
  2. Exclude organic causes of behavioural change
  3. Inform safety planning

Assessment Tools

ToolPurpose
Strengths and Difficulties Questionnaire (SDQ)Screening; parent/teacher/self-report
Conners' Rating ScalesADHD assessment
Beck Youth InventoriesDepression/anxiety
Inventory of Callous-Unemotional Traits (ICU)CU traits assessment
SAVRYRisk assessment (Structured Assessment of Violence Risk in Youth)

Medical Investigations (If Indicated)

InvestigationIndication
TFTsThyroid dysfunction affecting behaviour
FBC, U&EGeneral health screen
Urine drug screenIf substance misuse suspected
EEGIf seizure disorder suspected
Neuropsychological testingLearning difficulties; IQ testing

7. Management

Management Algorithm

              CONDUCT DISORDER MANAGEMENT
                         ↓
┌──────────────────────────────────────────────────────────────┐
│                   ASSESSMENT                                  │
├──────────────────────────────────────────────────────────────┤
│  ➤ Comprehensive psychiatric assessment                      │
│  ➤ Identify CU traits (DSM-5 specifier)                      │
│  ➤ Assess for comorbidities (ADHD, depression, LD)          │
│  ➤ Risk assessment (harm to self/others)                    │
│  ➤ Family and school assessment                              │
└──────────────────────────────────────────────────────────────┘
                         ↓
┌──────────────────────────────────────────────────────────────┐
│        FIRST-LINE: PARENTING INTERVENTIONS                   │
├──────────────────────────────────────────────────────────────┤
│  AGE &lt;12 YEARS:                                               │
│  ➤ Parent Training Programmes (PTP):                         │
│    • Webster-Stratton (Incredible Years)                     │
│    • Triple P (Positive Parenting Programme)                 │
│    • Parent-Child Interaction Therapy (PCIT)                 │
│                                                               │
│  Focuses on:                                                  │
│  • Positive reinforcement of good behaviour                  │
│  • Consistent limit-setting                                  │
│  • Reducing coercive interactions                            │
│  • Improving parent-child relationship                       │
└──────────────────────────────────────────────────────────────┘
                         ↓
┌──────────────────────────────────────────────────────────────┐
│      SECOND-LINE: CHILD-FOCUSED INTERVENTIONS                │
├──────────────────────────────────────────────────────────────┤
│  AGE &gt;12 YEARS OR INADEQUATE RESPONSE:                       │
│  ➤ Multi-Systemic Therapy (MST)                              │
│    • Intensive, community-based                               │
│    • Addresses family, peer, school, community               │
│    • Therapists available 24/7                               │
│    • 3-5 months duration                                     │
│                                                               │
│  ➤ Cognitive Behavioural Therapy (CBT)                       │
│    • Problem-solving skills training                         │
│    • Anger management                                        │
│    • Social skills training                                  │
│                                                               │
│  ➤ Multidimensional Treatment Foster Care (MTFC)             │
│    • For severe cases; trained foster families               │
└──────────────────────────────────────────────────────────────┘
                         ↓
┌──────────────────────────────────────────────────────────────┐
│              PHARMACOTHERAPY (ADJUNCTIVE)                    │
├──────────────────────────────────────────────────────────────┤
│  ➤ No medication licensed specifically for CD               │
│  ➤ Treat comorbidities:                                      │
│    • ADHD: Methylphenidate, atomoxetine                      │
│    • Depression: SSRIs                                        │
│    • Aggression (severe): Risperidone (off-label; short-term)│
│                                                               │
│  ⚠️ Antipsychotics for aggression only as last resort;       │
│     monitor metabolic effects                                │
└──────────────────────────────────────────────────────────────┘
                         ↓
┌──────────────────────────────────────────────────────────────┐
│                OTHER INTERVENTIONS                           │
├──────────────────────────────────────────────────────────────┤
│  ➤ School liaison and educational support                   │
│  ➤ Social services involvement (safeguarding)               │
│  ➤ Youth offending team (if criminal justice involvement)   │
│  ➤ Substance misuse services (if applicable)                │
└──────────────────────────────────────────────────────────────┘

Evidence-Based Parenting Programmes

ProgrammeAgeDescription
Incredible Years (Webster-Stratton)3-12Group-based; video modelling; focuses on positive parenting
Triple P0-16Multi-level; universal to intensive
Parent-Child Interaction Therapy (PCIT)2-7Live coaching of parent-child interactions

8. Complications

Short-Term Complications

ComplicationNotes
School exclusionDisruption to education; further marginalisation
Criminal justice involvementYouth offending; detention
Substance misuseHigh comorbidity
Self-harm/suicideDepression comorbidity
Family breakdownStrain on parents and siblings

Long-Term Outcomes

OutcomeRisk
Antisocial Personality Disorder~40% of childhood-onset CD
CriminalityIncreased arrest and conviction rates
Substance use disordersHigher rates
Poor educational attainmentSchool disruption
UnemploymentDifficulty maintaining employment
Relationship difficultiesIntimate partner violence

9. Prognosis & Outcomes

Prognostic Factors

Good PrognosisPoor Prognosis
Adolescent-onsetChildhood-onset
Absence of CU traitsCallous-unemotional traits
Limited/mild behavioursSevere/violent behaviours
Good parental engagementParental psychopathology
No comorbid ADHDComorbid ADHD
Access to treatmentLimited access to services

Outcomes by Onset Type

OnsetOutcome
Childhood-onset (<10 years)More persistent; higher rate of adult antisocial behaviour; more severe
Adolescent-onset (>10 years)Often linked to peer influence; more likely to desist in adulthood

10. Evidence & Guidelines

Key Guidelines

GuidelineOrganisationYearKey Points
Antisocial behaviour and conduct disorders (CG158)NICE2013 (updated 2017)Parent training; MST; pharmacotherapy guidance
ICD-11WHO2022Diagnostic classification
DSM-5APA2013CU trait specifier

Key Research

Webster-Stratton Parenting Programmes

  • Multiple RCTs show effectiveness in reducing conduct problems
  • Improves parent-child interaction
  • NNT ~3-5 for clinically significant improvement
  • PMID: 23165355

Multi-Systemic Therapy (MST)

  • RCTs show reduced re-arrest rates and out-of-home placements
  • Intensive but cost-effective
  • PMID: 16803502

11. Patient/Layperson Explanation

What is Conduct Disorder?

Conduct disorder is a condition where a young person repeatedly behaves in ways that break rules, hurt others, or damage property. It's more than just being "naughty" — it's a pattern of behaviour that causes real problems at home, school, or in the community.

What are the signs?

Signs include:

  • Getting into a lot of fights
  • Bullying or being cruel to people or animals
  • Destroying property or stealing
  • Running away from home or skipping school frequently
  • Lying often or breaking serious rules

What causes it?

There's no single cause. It's usually a combination of:

  • Genetics
  • Difficult family situations (harsh parenting, conflict)
  • Problems at school
  • Influence from peers who also misbehave

How is it treated?

Treatment focuses on:

  • Parent training programmes: Teaching parents positive ways to manage behaviour
  • Family therapy: Improving family relationships and communication
  • Therapy for the young person: Learning to manage anger and make better decisions
  • School support: Extra help with education and behaviour at school

Will it get better?

With the right support, many young people improve. Early intervention is key. Some young people grow out of it, especially if the behaviour started in adolescence rather than childhood.


12. References

Guidelines

  1. NICE. Antisocial behaviour and conduct disorders in children and young people: recognition and management (CG158). 2013 (updated 2017). nice.org.uk/guidance/cg158

Key Studies

  1. Webster-Stratton C, Reid MJ, Hammond M. Treating children with early-onset conduct problems: intervention outcomes for parent, child, and teacher training. J Clin Child Adolesc Psychol. 2004;33(1):105-124. PMID: 15028546

  2. Henggeler SW, Schoenwald SK, Borduin CM, et al. Multisystemic Treatment of Antisocial Behavior in Children and Adolescents. Guilford Press. 1998.


13. Examination Focus

High-Yield Exam Topics

TopicKey Points
ODD vs CDODD is defiant/angry; CD adds aggression, destruction, theft, rule violations
CD → ASPDCD is required before 15 for ASPD diagnosis
Callous-unemotional traitsLack of guilt/empathy; poor prognosis; DSM-5 specifier
Childhood vs adolescent onsetChildhood-onset has worse prognosis
First-line treatmentParent training programmes (Incredible Years, Triple P)
MSTIntensive community-based treatment for severe cases

Sample Viva Questions

Q1: How do you differentiate Oppositional Defiant Disorder from Conduct Disorder?

Model Answer: ODD is characterised by angry/irritable mood, argumentative/defiant behaviour, and vindictiveness. The behaviours are oppositional but do not involve aggression towards people or animals, destruction of property, or serious rule violations. CD is more severe and includes these features: physical aggression, cruelty to people or animals, destruction of property, deceitfulness/theft, and serious rule violations (truancy, running away). ODD is often considered a precursor to CD, though not all children with ODD progress to CD.

Q2: What are callous-unemotional traits and why are they important?

Model Answer: Callous-unemotional (CU) traits are a specifier in DSM-5 for conduct disorder. They include: lack of remorse or guilt, callousness/lack of empathy, unconcern about performance (school, work), and shallow or deficient affect. CU traits are important because they identify a subgroup with worse prognosis. These children have reduced response to standard treatments, are less sensitive to punishment, show reduced amygdala reactivity to fear cues, and are at higher risk of persistent antisocial behaviour into adulthood. They may require more intensive interventions.

Q3: What is the first-line management for a 7-year-old with conduct disorder?

Model Answer: According to NICE CG158, the first-line management for a child under 12 with conduct disorder is a group-based parent training programme. Evidence-based programmes include the Incredible Years (Webster-Stratton), Triple P, and PCIT. These programmes teach parents positive parenting strategies, consistent limit-setting, reducing coercive interactions, and strengthening the parent-child relationship. If parent training is insufficient, child-focused CBT (problem-solving, anger management) can be added. Medication is not first-line but may be considered for comorbidities such as ADHD.

Common Exam Errors

ErrorCorrect Approach
Diagnosing ASPD in a 16-year-oldASPD can only be diagnosed at ≥18 years; use CD for under-18s
Recommending medication first-linePsychological interventions are first-line; medication is adjunctive
Conflating ODD and CDODD is less severe; CD requires aggression/destruction/theft/rule violations
Missing CU trait specifierAlways assess for CU traits; changes prognosis and treatment approach

Last Reviewed: 2025-12-24 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists.

Last updated: 2025-12-24

At a Glance

EvidenceHigh
Last Updated2025-12-24

Red Flags

  • Precursor to Antisocial Personality Disorder
  • Callous-unemotional traits (poor prognosis)
  • History of cruelty to animals or fire-setting
  • Comorbid substance misuse
  • Risk of harm to self or others

Clinical Pearls

  • **Red Flags — Urgent Assessment:**
  • - Cruelty to animals (marker of severity)
  • - Fire-setting with intent to harm
  • - Expressed intent to harm others
  • - Suicidal ideation (comorbidity)

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines