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Emergency Medicine
Cardiothoracic Surgery
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EMERGENCY

Cardiac Tamponade in Adults

Moderate EvidenceUpdated: 2024-12-21

On This Page

Red Flags

  • Beck's triad (hypotension, JVP elevation, muffled heart sounds)
  • Pulsus paradoxus greater than 10 mmHg
  • Electrical alternans on ECG
  • PEA arrest
  • Trauma with haemodynamic instability
Overview

Cardiac Tamponade in Adults

Clinical Overview

Summary

Cardiac tamponade is a life-threatening condition caused by accumulation of fluid in the pericardial space, leading to compression of the heart and impaired filling. It is a clinical diagnosis based on haemodynamic compromise — treat urgently with pericardiocentesis. Causes include malignancy, infection (TB, viral), post-MI, trauma, and iatrogenic (post-procedure). Even small effusions can cause tamponade if rapidly accumulating.

Key Facts

  • Definition: Pericardial fluid causing haemodynamic compromise
  • Beck's triad: Hypotension, Raised JVP, Muffled heart sounds
  • Pulsus paradoxus: SBP drop greater than 10 mmHg on inspiration
  • Treatment: Pericardiocentesis (urgent) or surgical drainage
  • Volume matters less than rate: Slow effusions may reach 1L+ without tamponade
  • PEA arrest: Tamponade is a reversible cause (4 Hs and 4 Ts)

Clinical Pearls

Beck's triad is specific but insensitive — you may not see all three

In trauma, tamponade is often from haemopericardium — may need thoracotomy

Electrical alternans (alternating QRS height) is classic but uncommon

Why This Matters Clinically

Tamponade is a treatable cause of PEA arrest and shock. Rapid recognition and drainage saves lives. Echocardiography is diagnostic but should not delay treatment if diagnosis is clinically clear.


2. Epidemiology

Causes

CauseExamples
MalignancyLung, Breast, Lymphoma (most common in developed countries)
InfectionTB (common globally), Viral, Bacterial
IatrogenicPost-cardiac surgery, Catheterisation, Pacemaker insertion
Post-MIVentricular rupture, Dressler's syndrome
TraumaPenetrating or blunt chest injury
AutoimmuneSLE, RA
UraemiaChronic kidney disease
Aortic dissectionExtension into pericardium
Idiopathic

Demographics

  • Any age
  • Malignancy more common in elderly
  • TB common in endemic areas

Pathophysiology

Mechanism

1. Pericardial Fluid Accumulation

  • Inflammatory, malignant, traumatic, or transudative
  • Rate of accumulation more important than volume

2. Increased Intrapericardial Pressure

  • Exceeds normal filling pressures
  • Right heart compressed first (thinner wall)

3. Impaired Cardiac Filling

  • Reduced diastolic filling
  • Equalisation of diastolic pressures across chambers
  • Reduced stroke volume

4. Compensatory Mechanisms

  • Tachycardia
  • Peripheral vasoconstriction
  • Eventually fail → Hypotension, Shock, PEA arrest

Pulsus Paradoxus

  • Normal: SBP drops less than 10 mmHg on inspiration
  • Tamponade: Drop greater than 10 mmHg
  • Mechanism: Increased venous return to RV on inspiration → RV expansion → LV compression (fixed pericardial space) → Reduced LV output

Why Rate Matters More Than Volume

ScenarioVolumeOutcome
Chronic effusion (slow)Greater than 1LMay be asymptomatic (pericardium stretches)
Acute haemopericardium100-200mlTamponade (pericardium cannot stretch)

Emergency Management

Cardiac Tamponade — Emergency Management

Clinical Diagnosis:

  • Beck's Triad: Hypotension + Elevated JVP + Muffled heart sounds
  • Pulsus paradoxus: SBP drop greater than 10 mmHg on inspiration
  • Tachycardia
  • Cool peripheries

Immediate Actions:

  1. Call for Help

    • Cardiology, Cardiothoracic surgery
    • Prepare for pericardiocentesis
  2. IV Access and Fluids

    • Fluid bolus may temporarily improve filling
    • Do NOT over-resuscitate — may worsen tamponade
  3. Avoid Positive Pressure Ventilation

    • Reduces venous return, worsens haemodynamics
    • Consider awake pericardiocentesis before intubation
  4. Pericardiocentesis

    • Subxiphoid approach (most common)
    • Ultrasound guided (if available)
    • Insert needle towards left shoulder at 45 degrees
    • Aspirate — even 30-50ml may dramatically improve haemodynamics
    • Consider leaving drain in situ
  5. Surgical Drainage

    • Indicated if: Purulent effusion, Trauma (haemopericardium), Recurrent effusion, Aortic dissection
    • Pericardial window or pericardiectomy

[!WARNING] In traumatic tamponade, pericardiocentesis is often only a temporising measure. Definitive treatment is thoracotomy.

PEA Arrest

  • Tamponade is one of the "4 Ts" (reversible cause)
  • Consider if PEA with distended neck veins
  • Emergency pericardiocentesis during CPR
  • May need resuscitative thoracotomy

Clinical Assessment

History

  • Dyspnoea — progressive
  • Chest discomfort — may be positional
  • Symptoms of underlying cause — fever (infection), weight loss (malignancy), recent procedure

Physical Examination

Beck's Triad:

  1. Hypotension (narrow pulse pressure)
  2. Elevated JVP (often very high)
  3. Muffled heart sounds

Pulsus Paradoxus:

  • Measure BP with cuff
  • Note SBP when first Korotkoff sound heard on expiration only
  • Note SBP when heard throughout respiratory cycle
  • Difference greater than 10 mmHg = positive

Other Signs:

  • Tachycardia
  • Cool, clammy peripheries
  • Reduced urine output
  • Kussmaul's sign (JVP rises on inspiration) — less common in tamponade

Investigations

Bedside

ECG:

  • Low voltage QRS
  • Electrical alternans (alternating QRS amplitude)
  • Sinus tachycardia
  • May have features of pericarditis (diffuse ST elevation, PR depression)

Echocardiography (POCUS):

  • Gold standard for diagnosis
  • Pericardial effusion (anechoic space)
  • Right atrial and RV diastolic collapse (specific for tamponade)
  • Dilated IVC with reduced respiratory variation
  • Swinging heart

Laboratory

TestPurpose
TroponinMyopericarditis
Inflammatory markersInfection
TFTsHypothyroidism (rare cause)
Autoimmune screenSLE, RA
Pericardial fluid analysisCell count, Protein, LDH, Glucose, Cytology, Culture, AFB

Imaging

CXR:

  • Cardiomegaly ("water bottle" heart) if large effusion
  • May be normal if acute

CT Chest:

  • Characterise effusion
  • Look for malignancy, dissection

Pericardial Effusion Classification

By Size (Echocardiography)

SizeDescription
SmallLess than 10mm echo-free space
Moderate10-20mm
LargeGreater than 20mm

By Haemodynamic Effect

StatusFeatures
Effusion without tamponadeNo haemodynamic compromise
Tamponade physiologyEcho signs of chamber collapse
Clinical tamponadeHaemodynamic compromise

By Aetiology

  • Transudative (HF, hypoalbuminaemia)
  • Exudative (infection, malignancy, autoimmune)
  • Haemorrhagic (trauma, post-MI rupture, dissection)

Treatment

Acute Management

1. Supportive Measures

  • IV fluids (cautious bolus)
  • Avoid positive pressure ventilation if possible
  • Inotropes (limited benefit but may temporise)

2. Pericardiocentesis

  • Indication: Clinical tamponade, haemodynamic compromise
  • Technique: Subxiphoid approach, ultrasound guidance
  • Drainage: May leave pigtail catheter for ongoing drainage

3. Surgical Options

ProcedureIndication
Pericardial windowRecurrent effusion, malignancy
PericardiectomyConstrictive pericarditis
ThoracotomyTrauma, post-MI rupture

Treatment of Underlying Cause

CauseTreatment
MalignancyOncology referral, chemotherapy, pericardial window
TBAnti-TB therapy
ViralNSAIDs, Colchicine
AutoimmuneSteroids, DMARDs
UraemiaDialysis
IatrogenicDrain and monitor

Post-Procedure

  • Repeat echo to confirm resolution
  • Investigate underlying cause
  • Consider pericardial window if recurrent

Complications

Of Tamponade

ComplicationFeatures
PEA arrestCardiovascular collapse
Multi-organ failureProlonged poor perfusion
DeathIf untreated

Of Pericardiocentesis

ComplicationPrevention
Cardiac punctureUltrasound guidance
PneumothoraxCorrect technique
ArrhythmiaMonitor
InfectionAseptic technique

Prognosis

Short-Term

  • Excellent if treated promptly
  • Dependent on underlying cause
  • Malignant effusions have poorer prognosis

Recurrence

  • Common with malignancy
  • Pericardial window reduces recurrence

Evidence & Guidelines

Key Guidelines

  1. ESC Guidelines for Pericardial Diseases (2015) — European standard
  2. AHA Scientific Statement on Pericardial Diseases

Evidence Base

  • Pericardiocentesis is standard of care for tamponade
  • Ultrasound guidance reduces complications
  • Surgical drainage preferred for traumatic and purulent effusions

Evidence Levels

InterventionLevel
Pericardiocentesis for tamponadeConsensus
Ultrasound guidance2a
Surgical drainage for trauma/purulentConsensus
Pericardial window for malignancy2b

Information for Patients

What is Cardiac Tamponade?

Cardiac tamponade happens when fluid builds up in the sac around your heart (the pericardium). This fluid presses on your heart and stops it from filling properly, which can be life-threatening.

What Are the Symptoms?

  • Shortness of breath
  • Chest discomfort
  • Feeling faint or dizzy
  • Fatigue

What Causes It?

  • Infection around the heart
  • Cancer
  • After heart surgery or procedures
  • Injury to the chest
  • Inflammation

How Is It Treated?

  • Draining the fluid — using a needle (pericardiocentesis) or surgery
  • Treatment of the underlying cause
  • Close monitoring

After Treatment

  • You will have repeat scans to check the fluid doesn't return
  • Treatment for whatever caused the fluid buildup
  • Follow-up with a cardiologist

References

Primary Guidelines

  1. Adler Y, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Eur Heart J. 2015;36(42):2921-64. PMID: 26320112

Last updated: 2024-12-21

At a Glance

EvidenceModerate
Last Updated2024-12-21
Emergency Protocol

Red Flags

  • Beck's triad (hypotension, JVP elevation, muffled heart sounds)
  • Pulsus paradoxus greater than 10 mmHg
  • Electrical alternans on ECG
  • PEA arrest
  • Trauma with haemodynamic instability

Clinical Pearls

  • Beck's triad is specific but insensitive — you may not see all three
  • In trauma, tamponade is often from haemopericardium — may need thoracotomy
  • Electrical alternans (alternating QRS height) is classic but uncommon
  • In **traumatic tamponade**, pericardiocentesis is often only a temporising measure. Definitive treatment is **thoracotomy**.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines