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Acute Low Back Pain

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Overview

Acute Low Back Pain

Quick Reference

Critical Alerts

  • Cauda equina syndrome is a surgical emergency: Saddle anesthesia, urinary retention, bilateral weakness
  • Red flags require urgent evaluation: Cancer, infection, fracture, neurological deficit
  • Most low back pain is benign and self-limited: 90% resolve within 6 weeks
  • Imaging rarely changes management initially: Reserve for red flags
  • Early mobilization improves outcomes: Avoid prolonged bed rest
  • Opioids should be avoided or used short-term only

Red Flags (TUNA FISH)

LetterRed Flag
TTrauma
UUnexplained weight loss
NNeurological deficit (bladder/bowel, weakness)
AAge >0 (new onset) or <18
FFever, IV drug use, recent infection
IImmunocompromise
SSteroid use (osteoporosis risk)
HHistory of cancer

Cauda Equina Syndrome Warning Signs

FindingAction
Saddle anesthesiaEmergent MRI, neurosurgery
Urinary retention or incontinenceEmergent MRI, neurosurgery
Fecal incontinenceEmergent MRI, neurosurgery
Bilateral leg weaknessEmergent MRI, neurosurgery
Rapidly progressive neurological deficitEmergent MRI, neurosurgery

Emergency Treatments

ConditionTreatment
Mechanical LBPNSAIDs + activity modification + PT referral
Radiculopathy (no red flags)NSAIDs + activity + PT; consider oral steroids
Cauda equina syndromeEmergent MRI → Surgical decompression
Spinal infection (epidural abscess)MRI + IV antibiotics + surgical consult
Metastatic spinal cord compressionMRI + steroids + oncology/neurosurgery

Definition

Overview

Acute low back pain (LBP) is pain in the lumbosacral region lasting less than 4 weeks. It is one of the most common reasons for ED visits and physician consultation. The key ED task is identifying the rare serious causes (cauda equina, cancer, infection, fracture) while appropriately managing the majority with reassurance, analgesia, and activity.

Classification

By Duration:

TypeDuration
Acute<4 weeks
Subacute4-12 weeks
Chronic>2 weeks

By Cause:

TypeFrequencyExamples
Mechanical (non-specific)~85%Muscle strain, ligament sprain, degenerative
Radiculopathy~5-10%Herniated disc, stenosis
Serious pathology<5%Cauda equina, cancer, infection, fracture

Epidemiology

  • Lifetime prevalence: 70-80%
  • Leading cause of disability worldwide
  • Peak age: 30-50 years
  • Recurrence common: ~25-50%

Etiology

Mechanical/Non-Specific (~85%):

CauseNotes
Muscle strainMost common
Ligament sprainLifting, twisting
Degenerative disc/joint diseaseOlder adults
SpondylolisthesisYoung athletes (pars defect)

Radiculopathy/Sciatica (~5-10%):

CauseMechanism
Herniated discNerve root compression
Spinal stenosisNeurogenic claudication

Serious Pathology (<5%):

CauseRed Flags
Cauda equina syndromeSaddle anesthesia, retention, bilateral symptoms
MalignancyWeight loss, history of cancer
Spinal infection (epidural abscess, discitis)Fever, IVDU, immunocompromise
FractureTrauma, osteoporosis, steroids
Abdominal aortic aneurysmPulsatile mass, hypotension

4. Pathophysiology

Mechanical LBP

  • Microtrauma to muscles, ligaments, discs
  • Inflammatory response → Pain, spasm
  • Usually self-limited

Radiculopathy

  • Herniated disc or bony stenosis compresses nerve root
  • L4-L5 and L5-S1 most common levels
  • Dermatomal pain, sensory/motor deficits

Cauda Equina Syndrome

  • Compression of cauda equina (nerve roots below conus)
  • Causes: Large disc herniation, tumor, abscess, hematoma
  • Results in bladder/bowel dysfunction, saddle anesthesia, weakness

5. Clinical Presentation

Symptoms

FindingMechanical LBPRadiculopathyCauda Equina
Pain distributionLocalized low backRadiates below knee (dermatomal)Bilateral leg pain
Neurological symptomsNoneSensory, motor (dermatomal)Saddle anesthesia, bladder/bowel
OnsetUsually after activityMay be gradual or suddenUsually rapid

History

Key Questions:

Physical Examination

General Exam:

FindingSignificance
FeverInfection
Weight lossMalignancy
Pulsatile abdominal massAAA

Spine Exam:

FindingSignificance
Midline tendernessFracture, infection
Paraspinal muscle spasmMechanical
Limited range of motionMechanical or serious
Step-off deformitySpondylolisthesis

Neurological Exam:

TestLevelFinding
Knee reflex (L4)L4Diminished = L4 radiculopathy
Ankle reflex (S1)S1Diminished = S1 radiculopathy
Great toe dorsiflexion (L5)L5Weak = L5 radiculopathy
Straight leg raise (SLR)SciaticPositive = Radiculopathy
Perianal sensationS2-S4Absent = Cauda equina
Rectal toneS2-S4Decreased = Cauda equina

Straight Leg Raise:


Onset, duration, character, radiation of pain
Common presentation.
Trauma?
Common presentation.
Red flag symptoms (weight loss, fever, bladder/bowel changes, weakness)
Common presentation.
History of cancer?
Common presentation.
IV drug use, recent infection?
Common presentation.
Steroid use, immunocompromise?
Common presentation.
Previous spinal surgery or injections?
Common presentation.
6. Clinical Examination

(Integrated into Clinical Presentation above)

Red Flags

Must Exclude Serious Pathology

Red FlagConcernAction
Saddle anesthesiaCauda equinaEmergent MRI
Urinary retention/incontinenceCauda equinaEmergent MRI
Bilateral leg weaknessCauda equinaEmergent MRI
FeverEpidural abscess, discitisMRI, blood cultures
IVDU, recent infectionEpidural abscessMRI
History of cancerMetastatic diseaseMRI, oncology
Unexplained weight lossMalignancyMRI
Age >0 with new LBPMalignancy, fractureConsider imaging
Severe traumaFractureX-ray/CT
Steroid use, osteoporosisFractureX-ray
Progressive neurological deficitCord/root compressionMRI

7. Investigations

Differential Diagnosis

DiagnosisFeatures
Renal colicColicky flank pain, hematuria
PyelonephritisFever, CVA tenderness, pyuria
Abdominal aortic aneurysmPulsatile mass, hypotension (if ruptured)
PancreatitisEpigastric pain radiating to back
GI pathologyAssociated with eating, bowel symptoms
Hip pathologyGroin/lateral pain, limited hip ROM
Herpes zosterDermatomal rash, pain precedes rash

Diagnostic Approach

Imaging Guidelines

Imaging NOT Indicated for Most Acute LBP:

  • No red flags = No imaging initially
  • Most acute LBP resolves in 4-6 weeks

When to Image:

IndicationModality
Red flags (cauda equina, cancer, infection)MRI
Severe trauma, fracture concernX-ray → CT if positive or high suspicion
Progressive neurological deficitMRI
Not improving after 6 weeks of conservative careMRI

Laboratory Studies

TestIndication
CBC, ESR, CRPSuspected infection or malignancy
Blood culturesSuspected epidural abscess
UrinalysisRule out renal pathology

8. Management

Principles

  1. Reassurance: Most LBP is benign and self-limited
  2. Activity: Early mobilization; avoid bed rest
  3. Analgesia: NSAIDs first-line; avoid opioids if possible
  4. Physical therapy: Referral for subacute/chronic cases
  5. Identify and emergently treat red flags

Analgesia

First-Line: NSAIDs:

AgentDose
Ibuprofen400-600 mg PO TID
Naproxen500 mg PO BID

Adjuncts:

AgentNotes
AcetaminophenLess effective than NSAIDs but useful
Muscle relaxants (short-term)Cyclobenzaprine 10 mg TID; sedating
Topical analgesicsLidocaine patch, diclofenac gel

Avoid/Minimize:

AgentReason
OpioidsNo long-term benefit; addiction risk
BenzodiazepinesNo evidence; sedation, dependence
Systemic steroidsNo benefit for non-radicular LBP

Radiculopathy Management

InterventionDetails
NSAIDsFirst-line
Activity modificationAvoid aggravating activities
Physical therapyCore strengthening, stretching
Oral steroids (short course)May provide short-term relief
Epidural steroid injectionFor refractory radiculopathy (specialist)
SurgeryFor progressive neurological deficit or failure of conservative management

Cauda Equina Syndrome

InterventionDetails
Emergent MRIConfirm diagnosis
Neurosurgical consultationUrgent
Surgical decompressionWithin 24-48 hours (ideally sooner)

Spinal Infection (Epidural Abscess, Discitis)

InterventionDetails
MRIImaging of choice
Blood culturesBefore antibiotics if possible
IV antibioticsBroad-spectrum (staph coverage: vancomycin + cefepime or pip-tazo)
Surgical drainageIf abscess, neurological deficit, or instability

Metastatic Spinal Cord Compression

InterventionDetails
MRI whole spineIdentify all metastases
Dexamethasone10 mg IV bolus → 4 mg q6h
Oncology/Radiation oncologyUrgent
NeurosurgeryIf surgical candidate

9. Complications

Disposition

Discharge Criteria

  • No red flags
  • Pain controlled
  • Able to ambulate
  • Reliable follow-up

Admission Criteria

  • Cauda equina syndrome
  • Epidural abscess
  • Metastatic spinal cord compression
  • Unstable spinal fracture
  • Unable to ambulate or care for self
  • Severe pain not controlled

Referral

IndicationReferral
Radiculopathy not improvingSpine surgery or PM&R
Chronic LBPPain management, physical therapy
Suspected malignancyOncology

Follow-Up

SituationFollow-Up
Mechanical LBPPCP in 1-2 weeks if not improving
RadiculopathySpecialist within 1-2 weeks
Post-hospitalizationSpine surgery/oncology as indicated

12. Patient/Layperson Explanation

Condition Explanation

  • "Low back pain is very common and usually not serious."
  • "Most cases improve within a few weeks with activity and medication."
  • "Staying active is better than bed rest."

Home Care

  • Use NSAIDs as directed
  • Apply ice or heat for comfort
  • Stay active; gentle walking and stretching
  • Avoid lifting heavy objects
  • Maintain good posture

Warning Signs to Return

  • Numbness in groin or inner thighs (saddle area)
  • Difficulty urinating or loss of bowel control
  • Weakness in legs or feet getting worse
  • Fever or chills
  • Unexplained weight loss

10. Prognosis & Outcomes

Special Populations

Elderly

  • Higher risk of serious pathology (cancer, fracture)
  • Lower threshold for imaging
  • More cautious with NSAIDs (renal, GI, CV risk)

Cancer History

  • Any new LBP is metastatic disease until proven otherwise
  • MRI of entire spine

Osteoporosis/Steroid Use

  • Vertebral compression fractures
  • X-ray initially; MRI if neurological symptoms

Pregnancy

  • Avoid NSAIDs (especially 3rd trimester)
  • Acetaminophen for analgesia
  • Physical therapy helpful

Quality Metrics

Performance Indicators

MetricTargetRationale
Red flag documentation100%Identify serious causes
Neurological exam documented100%Detect cauda equina
Avoid imaging without red flags>0%Reduce unnecessary radiation
NSAIDs as first-line>0%Guideline adherence
Avoid opioids for acute LBP>0%Prevent opioid misuse

Documentation Requirements

  • Red flag assessment
  • Neurological exam (strength, reflexes, sensation)
  • Rectal tone and saddle sensation (if cauda equina suspected)
  • Imaging rationale (if performed)
  • Discharge instructions

11. Evidence & Guidelines

Key Clinical Pearls

Diagnostic Pearls

  • Cauda equina = Emergent MRI: Don't miss bladder/bowel symptoms
  • Red flags guide imaging: Most acute LBP doesn't need imaging
  • SLR is sensitive for radiculopathy: Crossed SLR is more specific
  • Check perianal sensation and rectal tone: For cauda equina
  • Age >50 + new LBP: Consider malignancy/fracture
  • IVDU + back pain + fever = Epidural abscess: MRI urgently

Treatment Pearls

  • NSAIDs are first-line: Better than acetaminophen alone
  • Muscle relaxants are adjuncts: Short-term only; sedating
  • Avoid opioids: No long-term benefit; addiction risk
  • Early activity is key: Bed rest worsens outcomes
  • Steroids only for radiculopathy: Not for mechanical LBP
  • PT referral for subacute/chronic: Core strengthening

Disposition Pearls

  • Most can be discharged: With reassurance and analgesia
  • Admit for red flags: Cauda equina, abscess, cancer
  • Follow-up in 1-2 weeks: If not improving
  • Specialist for radiculopathy not improving: 4-6 weeks

13. References
  1. Qaseem A, et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain. Ann Intern Med. 2017;166(7):514-530.
  2. Chou R, et al. Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline. Ann Intern Med. 2007;147(7):478-491.
  3. Deyo RA, et al. Low Back Pain. N Engl J Med. 2001;344(5):363-370.
  4. Jarvik JG, et al. Diagnostic imaging for low back pain. Ann Intern Med. 2002;137(7):586-597.
  5. Kreiner DS, et al. An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy. Spine J. 2014;14(1):180-191.
  6. Casazza BA. Diagnosis and treatment of acute low back pain. Am Fam Physician. 2012;85(4):343-350.
  7. NICE Guideline. Low back pain and sciatica in over 16s: assessment and management. 2016.
  8. UpToDate. Evaluation of low back pain in adults. 2024.

At a Glance

EvidenceStandard
Last UpdatedRecently

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines